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Stevioside

pharmaceutical raw materials
Stevioside structure

Stevioside 

structure
  • CAS No:

    57817-89-7

  • Formula:

    C38H60O18

  • Chemical Name:

    Stevioside

  • Synonyms:

    Kaur-16-en-18-oic acid,13-[(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-,β-D-glucopyranosyl ester,(4α)-;Stevioside;1H-2,10a-Ethanophenanthrene,kaur-16-en-18-oic acid deriv.;Steviosin;α-G-Sweet;Stevian 50;E 960;1,2-Stevioside;138395-02-5;77-05-4;82080-10-2;474452-32-9

  • Categories:

    Cosmetic Ingredient  >  Oral Care

Description

Stevioside is a natural sweetener extracted from leaves of Stevia rebaudiana, with anticancer activity[1].


Solid


Stevioside is a diterpene glycoside that is rubusoside in which the hydroxy group at position 2 of the allylic beta-D-glucoside has been converted to the corresponding beta-D-glucoside. It is a natural herbal sweetener that is 250-300 times sweeter than sucrose (though with a bitter aftertaste), extracted from the Stevia rebaudiana plant native to South America. It has a role as a sweetening agent, an antioxidant, an antineoplastic agent, a hypoglycemic agent, an anti-inflammatory agent and a plant metabolite. It is a diterpene glycoside, an ent-kaurane diterpenoid, a beta-D-glucoside, a tetracyclic diterpenoid and a bridged compound. It derives from a steviol and a rubusoside.

Stevioside Basic Attributes

804.87200

804.87

260-975-5

0YON5MXJ9P

DTXSID7021281

2938909090

Characteristics

294.98000

-2.93810

Solid

1.53g/cm3

198 °C

963.3ºC at 760 mmHg

290.3ºC

-39.3 ° (C=6, H2O)

1.25 mg/mL

0-6ºC

269.64 Ų [M+H]+ [CCS Type: TW]

Safety Information

NONH for all modes of transport

3

S22; S24/25

NZ8175000

Drug Information

Substances that sweeten food, beverages, medications, etc., such as sugar, saccharine or other low-calorie synthetic products. (From Random House Unabridged Dictionary, 2d ed) (See all compounds classified as Sweetening Agents.)

steviol glycoside

Stevioside Use and Manufacturing

Uses

1. Stevioside is a glycoside from the stevia plant. Stevioside is a natural sweetening agent with sweetness about 250 times that of sugar with negligible effect on blood glucose. Stevioside, much like other steviol glycoside is known for its application in treatment of many diseases like diabetes and high blood pressure. It is also used as a food additive and in dietary supplements.
2. Sweetener

Cosmetics -> Masking; Oral care

Computed Properties

Molecular Weight:804.9
XLogP3:-1.2
Hydrogen Bond Donor Count:11
Hydrogen Bond Acceptor Count:18
Rotatable Bond Count:10
Exact Mass:804.37796506
Monoisotopic Mass:804.37796506
Topological Polar Surface Area:295
Heavy Atom Count:56
Complexity:1450
Defined Atom Stereocenter Count:21
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Natural sweetener derived from Stevia plant; non-caloric and does not affect blood glucose levels.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Registered Holders

  • Tianjin Nanda Kaitai Pharmaceutical Co., Ltd.

    China China
    Active
  • Sichuan Boliheng Pharmaceutical Co., Ltd.

    China China
    Active
  • Shanxiyulongpharmaceutical Co., Ltd.

    China China
    Active

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