α-Cyclodextrin
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α-Cyclodextrin
structure -
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CAS No:
10016-20-3
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Formula:
C36H60O30
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Chemical Name:
α-Cyclodextrin
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Synonyms:
α-Cyclodextrin;Cyclohexaamylose;2,4,7,9,12,14,17,19,22,24,27,29-Dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane,α-cyclodextrin deriv.;Dextrin,α-cyclo;α-Schardinger dextrin;Cyclomaltohexaose;Cyclomaltohexose;α-Dextrin;α-Cycloamylose;Stereoisomer of 5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol;Cyclohexadextrin;Alfadex;Ringdex A;Celdex A 100;Dexy Pearl α-100;NSC 269470;Cavamax W 6;Cavamax W 6 Food;Isoeleat K 50;α-100;Dexipar α-100;23513-50-0;41871-62-9;47910-04-3;1229648-14-9;1244024-89-2;2095261-37-1
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CAS No:
Description
White crystalline powder Cyclodextrins occur as white, practically odorless, fine crystalline powders, having a slightly sweet taste. Some cyclodextrin derivatives occur as amorphous powders.Hexagonal plates or blade-shaped needles.
Hexagonal plates or blade-shaped needles. (NTP, 1992)|DryPowder
Hexagonal plates or blade-shaped needles. (NTP, 1992)
Characteristics
474.90000
-13.05480
white powder
1.624 g/cm3
278ºC
1410.8ºC at 760 mmHg
807.1ºC
1.591
H2O: 50 mg/mL
Store at RT.
0mmHg at 25°C
No rapid reaction with air. No rapid reaction with water.
Alcohols and Polyols
ALPHA-CYCLODEXTRIN has hydrophobic cavities. It forms inclusion compounds with organic substances, salts, and halogens in the solid state or in aqueous solutions. It is incompatible with strong oxidizing agents. (NTP, 1992)
Safety Information
NONH for all modes of transport
3
R36
S26; S36
GU2292000
Xi
Cyclodextrins should be stored in a tightly sealed container, in a cool, dry place.Cyclodextrins are stable in the solid state if protected from high humidity.
Stable. Combustible. Incompatible with strong oxidizing agents.
Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Not Classified
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
SMALL SPILLS AND LEAKAGE: If you should spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. You should then use absorbent paper to pick up liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent-wash contaminated surfaces with 60-70% methanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this chemical under ambient temperatures, and keep it away from oxidizing materials. (NTP, 1992)
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)
Drug Information
SYMPTOMS: A symptom of exposure to this chemical is irritation. ACUTE/CHRONIC HAZARDS: This compound may be harmful by inhalation, ingestion, or skin absorption. It may cause irritation. When heated to decomposition this compound emits toxic fumes of carbon monoxide and carbon dioxide. (NTP, 1992)
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
alpha-cyclodextrin
α-Cyclodextrin Use and Manufacturing
Supramolecular carriers, complexing agent, controlled drug release.
Agricultural chemicals (non-pesticidal)
Agricultural products (non-pesticidal)
Agriculture, forestry, fishing and hunting|.alpha.-Cyclodextrin: ACTIVE
Computed Properties
Molecular Weight:972.8
XLogP3:-12.9
Hydrogen Bond Donor Count:18
Hydrogen Bond Acceptor Count:30
Rotatable Bond Count:6
Exact Mass:972.31694049
Monoisotopic Mass:972.31694049
Topological Polar Surface Area:475
Heavy Atom Count:66
Complexity:1250
Defined Atom Stereocenter Count:12
Undefined Atom Stereocenter Count:18
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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