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Prochloraz

Prochloraz structure

Prochloraz 

structure
  • CAS No:

    67747-09-5

  • Formula:

    C15H16Cl3N3O2

  • Chemical Name:

    Prochloraz

  • Synonyms:

    1H-Imidazole-1-carboxamide,N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-;N-Propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide;BTS 40542;Prochloraz;BTS 40542-7877;Sportak;KI 835;Prelude;DMI;Sportake;Mirage;Mirage (pesticide);Plocloraz;N-Propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]imidazole-1-carboxamide;68444-81-5;1135441-21-2

  • Categories:

    Agrochemicals  >  Fungicides

Description

Prochloraz is an imidazole fungicide that is widely used in Europe, Australia, Asia and South America within gardening and agriculture
[1, 2]
. It is used on wheat, barley, mushrooms, cherries, turf on golf courses, and in flower production, for instance, in Ecuador, where roses are treated with prochloraz prior to export to the USA
[1, 2]
. It was first evaluated by JMPR in 1983 for residues and toxicology, and subsequently six additional reviews of residues have been carried o


Prochloraz is a member of the class of ureas that is 1H-imidazole-1-carboxamide substituted by a propyl and a 2-(2,4,6-trichlorophenoxy)ethyl group at the amino nitrogen atom. A fungicide active against a wide range of diseases affecting field crops, fruit, turf and vegetables. It has a role as a xenobiotic, an environmental contaminant, an EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor and an antifungal agrochemical. It is an aromatic ether, a trichlorobenzene, a member of ureas, a member of imidazoles, an amide fungicide, a conazole fungicide and an imidazole fungicide.

Prochloraz Basic Attributes

376.66500

376.67

266-994-5

99SFL01YCL

DTXSID4024270

2933290012

Characteristics

47.36000

4.60240

colorless solid

1.37 g/cm3

48 °C

209 °C

256.1ºC

1.596

9.10e-03 g/l

0-6ºC

1.5 x l0 -4 Pa (25 °C)

LD50 in rats (mg/kg): 1600 orally; >5000 s.c.; 400-800 i.p.; LC50 (96 hour) in rainbow trout, bluegill (mg/l): 1, 2.2 (de Saint-Blanquat, My)

Safety Information

III

UN 3077

3

R22; R50/53

S60-S61

NI4000400

Xn

Stable at normal temperatures and pressures.

P273-P501

H302-H410

|Warning|H302: Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P273, P301+P312, P330, P391, and P501|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|Aggregated GHS information provided by 399 companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H303: May be harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P260, P264, P270, P281, P308+P313, P309+P311, P312, P314, P405, and P501

Toxicity

501.19 L/kg

Drug Information

Chemicals that kill or inhibit the growth of fungi in agricultural applications, on wood, plastics, or other materials, in swimming pools, etc. (See all compounds classified as Fungicides, Industrial.)

Carcinogens

N-propyl-N-(2-(2,4,6-trichlorophenoxy)ethyl)-1H-imidazole

Prochloraz Use and Manufacturing

Uses

Plocloraz is used as a fungicide. Plocloraz showed efficacy against cereal powdery mildew. It can prevent and treat many diseases of cereal crops, field crops, fruit trees, vegetables, etc., such as rice blast, other leaf spot diseases and powdery mildew.

Agrochemicals -> Fungicides|Health Hazards -> Carcinogens|Pharmaceuticals|Fungicides|Environmental transformation -> Pesticides (parent, predecessor)

Prochloraz has known environmental transformation products that include N-formyl-N'-propyl-N'-2(2,4,6-trichlorophenoxy)ethylurea.|Prochloraz has known environmental transformation products that include BTS 44 595, BTS 44 596, BTS 45 186 (2,4,6-trichlorophenol), and Imidazole.

Computed Properties

Molecular Weight:376.7
XLogP3:4.6
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:375.030810
Monoisotopic Mass:375.030810
Topological Polar Surface Area:47.4
Heavy Atom Count:23
Complexity:377
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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