Sodium carboxymethyl starch
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Sodium carboxymethyl starch
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CAS No:
9063-38-1
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Formula:
C2H4O3.xNa.xUnspecified
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Chemical Name:
Sodium carboxymethyl starch
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Synonyms:
Starch,carboxymethyl ether,sodium salt;Sodium carboxymethyl starch;Carboxymethyl starch sodium salt;Sodium starch glycolate;Primojel;Sodium CM-starch;Solvitose CL;Explotab;Estarl A 100;Kiprogum F 500;Emsize CMS 60;Emsize CMS 100;Polvitex Z;Papeal F 500 No. 50;F 500 Papeal No. 50;Deprogel;Polytex 60;Vivastar P 5000;Explosol;Vivastar P;Crayon B 300P;LCW Covagel;Walocel CRT 100GA;Explotab CL-V;Libeng;Glycolys LV;Vivastar P 3500;WS 1R;Glycol YS;KMK-OK;KMK-BUR 1;Covagel;P 5000;Glycolys Std;Expotab PCF;Vivastar;Viva Star P 5E;Emsize CMS 150;Promogel;Glucosol 1148;Explotab PCF;9061-71-6;60351-56-6;65931-51-3
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CAS No:
Description
White or almost white, fine, free-flowing powder, very hygroscopic. Sodium starch glycolate is a white or almost white free-flowing very hygroscopic powder. The PhEur 6.0 states that when examined under a microscope it is seen to consist of: granules, irregularly shaped, ovoid or pear-shaped, 30–100 mm in size, or rounded, 10–35 mm in size; compound granules consisting of 2–4 components occur occasionally; the granules have an eccentric hilum and clearly visible concentric striations. Between c
Characteristics
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Tablets prepared with sodium starch glycolate have good storage
properties. Sodium starch glycolate is stable although very
hygroscopic, and should be stored in a well-closed container in
order to protect it from wide variations of humidity and
temperature, which may cause caking.
The physical properties of sodium starch glycolate remain
unchanged for up to 3 years if it is stored at moderate temperatures
and humidity.
Sodium carboxymethyl starch Use and Manufacturing
Sodium starch glycolate is widely used in oral pharmaceuticals as a disintegrant in capsule and tablet formulations. It is recommended to use in tablets prepared by either directcompression or wet-granulation processes.
Drug Function and Efficacy
Not yet clear
Registered Holders
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HUZHOU ZHANWANG PHARMACEUTICAL CO LTD
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United States
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DFE PHARMA GMBH AND CO KG
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United States
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YUNG ZIP CHEMICAL IND. CO., LTD.
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Taiwan, China
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