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Bistris

Bistris structure

CAS No:
6976-37-0
Formula:
C8H19NO5
Chemical Name:
Bistris
Synonyms:
1,3-Propanediol,2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-;2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol;2,2-Bis(hydroxymethyl)-2,2′,2′′-nitrilotriethanol;Bistris;NSC 119932;NSC 24868;NuPage Bis-Tris
Categories:
Cosmetic Ingredient > Buffering

Description

White/clear crystalline powder

Liquid

Bis-tris is a buffer substance useful for calibration of glass electrodes and for the preparation of the biochemical and biological buffer solutions; pKa = 6.46 at 25 ℃. It has a role as a buffer. It derives from a member of tris.

Bistris Basic Attributes

Molecular Weight：

209.24000

Exact Mass：

209.24

EC Number：

230-237-7

UNII：

Q1XC3631CP

NSC Number：

119932|24868

DSSTox ID：

DTXSID6064537

HScode：

29221980

Characteristics

PSA：

104.39000

XLogP3：

-3.3

Appearance：

Liquid

Density：

1.346 g/cm3

Melting Point：

103-104ºC

Boiling Point：

466.2ºC at 760 mmHg

Flash Point：

288ºC

Refractive Index：

1.563

Water Solubility：

H2O: soluble

Storage Conditions：

Store at RT.

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

R21/22; R36/37/38

safety instructions：

S22-S26-S36/37/39

Marks：

Precautionary statement(s)：

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

Hazard Statements：

H315

GHS Classification：

|Danger|H315 (68.72%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 181 companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 116 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH：

A chemical system that functions to control the levels of specific ions in solution. When the level of hydrogen ion in solution is controlled the system is called a pH buffer. (See all compounds classified as Buffers.)

MeSH Entry Terms：

2-(bis(2-hydroxyethyl)amino)-2(hydroxymethyl)-1,3-propanediol

Bistris Use and Manufacturing

Uses

Bis-tris methane is a buffering agent used in biochemistry. Bis-tris methane is an organic tertiary amine with labile protons having a pKa of 6.46 at 25°C. It is an effective buffer between the pH 5.8 and 7.3.

Manufacturing Info：

1,3-Propanediol, 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-: ACTIVE

Computed Properties

Molecular Weight:209.24
XLogP3:-3.3
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:209.12632271
Monoisotopic Mass:209.12632271
Topological Polar Surface Area:104
Heavy Atom Count:14
Complexity:125
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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7601-54-9
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Guide of Bistris

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
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