Dronedarone hydrochloride
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Dronedarone hydrochloride
structure -
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CAS No:
141625-93-6
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Formula:
C31H44N2O5SClH
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Chemical Name:
Dronedarone hydrochloride
- Categories:
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CAS No:
Description
Dronedarone hydrochloride is a non-iodinated amiodarone derivative that inhibits Na+, K+ and Ca2+ currents.
Characteristics
97.2
9.00480
white to off-white
NA (low-melting)
683.9ºC at 760mmHg
367.4ºC
DMSO: soluble15mg/mL, clear
Refrigerator
1.47E-18mmHg at 25°C
Safety Information
UN 3077 9 / PGIII
P201, P202, P260, P261, P263, P264, P270, P271, P273, P280, P281, P301+P312, P302+P352, P304+P340, P305+P351+P338, P308+P313, P312, P321, P330, P332+P313, P337+P313, P362, P391, P403+P233, P405, P501
H302
|Danger|H302 (33.33%): Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P260, P261, P263, P264, P270, P271, P273, P280, P281, P301+P312, P302+P352, P304+P340, P305+P351+P338, P308+P313, P312, P321, P330, P332+P313, P337+P313, P362, P391, P403+P233, P405, and P501|Aggregated GHS information provided by 13 companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Dronedarone hydrochloride Use and Manufacturing
A drug used for the treatment of atrial fibrillation and atrial flutter in patients who have suffered cardiac arrhythmias.
Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
Computed Properties
Molecular Weight:593.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:18
Exact Mass:592.2737714
Monoisotopic Mass:592.2737714
Topological Polar Surface Area:97.2
Heavy Atom Count:40
Complexity:800
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Not yet clear
Registered Holders
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AURORE LIFE SCIENCES PRIVATE LTD
Active
United States
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RAKS PHARMA PVT LTD
Active
United States
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MSN LABORATORIES PRIVATE LTD
Active
United States
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