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Chlorhexidine gluconate

Chlorhexidine gluconate structure

CAS No:
18472-51-0
Formula:
C22H30Cl2N10.2C6H12O7
Chemical Name:
Chlorhexidine gluconate
Synonyms:
D-Gluconic acid,compd. with N1,N14-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide (2:1);Gluconic acid,compd. with 1,1′-hexamethylenebis[5-(p-chlorophenyl)biguanide] (2:1),D-;D-Gluconic acid,compd. with N,N′′-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide (2:1);D-Gluconic acid,compd. with 1,1′-hexamethylenebis[5-(p-chlorophenyl)biguanide] (2:1);Biguanide,1,1′-hexamethylenebis[5-(p-chlorophenyl)-,di-D-gluconate;2,4,11,13-Tetraazatetradecanediimidamide,N,N′′-bis(4-chlorophenyl)-3,12-diimino-,di-D-gluconate;1,6-Bis(4-chlorophenyldiguanino)hexane digluconate;Chlorhexidine digluconate;1,6-Bis(p-chlorophenyldiguanido)hexane digluconate;Bis(p-chlorophenyl)diguanidohexane digluconate;Chlorhexidine gluconate;1,6-Bis[N5-(p-chlorophenyl)biguanido]hexane digluconate;1,1′-Hexamethylenebis[5-(p-chlorophenyl)biguanide] digluconate;Chlorhexidine di-D-gluconate;Hibiscrub;Arlacide G;Disteryl;Abacil;Corsodyl;Hibitane;Septeal;Peridex;Hibitane 5;Peridex (antiseptic);Chlorhexidine bigluconate;Hexidine;Hibisol;Maskin;Maskin R;Manusan;SY 1007;Betasept;Hibistat;Geksikon;Blue Ribbon Sanitizing Teat Dip;Sterilon;Chlorhexamed;Rotersept;Hibital;PHiso-Med;Plac Out;Hibidil;Unisept;Bacticlens;Gingisan;Secalan;PerioChip;Akhdez 3000;CHG Solution BP;Oramed;Hexicon;Hibitane G;Permachem CL 40;Chloraprep;Antiseptol;Purit;Hexana;Acclean;Medihex-4;Dentochlor;105791-72-8;124973-71-3;12068-31-4;14007-07-9;21293-24-3;23289-58-9;40330-16-3;51365-13-0;52196-45-9;52387-19-6;60042-57-1;60404-86-6;82432-16-4;452971-25-4;150621-85-5;151498-43-0;227749-99-7;230296-52-3;906339-38-6
Categories:
Cosmetic Ingredient > Cosmetic Preservative

Description

Chlorhexidine is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms.Target: AntibacterialChlorhexidine is a chemical antiseptic.It is effective on both Gram-positive and Gram-negative bacteria, although it is less effective with some Gram-negative bacteria.It has both bactericidal and bacteriostatic mechanisms of action, the mechanism of action being membrane disruption, not ATPase inactivation as previously thought.It is also useful against fungi

Chlorhexidine gluconate Basic Attributes

Molecular Weight：

897.75700

Exact Mass：

896.32000

HScode：

3004909090

Characteristics

PSA：

444.48000

XLogP3：

-0.70240

Appearance：

Colorless to Pale Yellow Clear Liquid

Density：

1.06 (20% aq.)

Melting Point：

134ºC

Boiling Point：

699.3ºC at 760 mmHg

Flash Point：

376.7ºC

Storage Conditions：

2-8ºC

Vapor Pressure：

0mmHg at 25°C

Safety Information

Transport codes：

UN 3082 9 / PGIII

wgk germany：

hazard class code：

50/53

safety instructions：

Marks：

Precautionary statement(s)：

P273-P501

Hazard Statements：

H410

Drug Information

Drug Indication：

Prevention of infection prior to invasive procedures|Prevention of infections prior to invasive procedures

Chlorhexidine gluconate Use and Manufacturing

Uses

Hydrogenolysis of benzyl-nitrogen bonds

Use Classification：

Human Drugs -> EU pediatric investigation plans

Computed Properties

Molecular Weight:897.8
Hydrogen Bond Donor Count:18
Hydrogen Bond Acceptor Count:16
Rotatable Bond Count:23
Exact Mass:896.3198018
Monoisotopic Mass:896.3198018
Topological Polar Surface Area:455
Heavy Atom Count:60
Complexity:819
Defined Atom Stereocenter Count:8
Undefined Bond Stereocenter Count:2
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Broad spectrum fungicide

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Metronidazole chlorhexidine lotion
Ingredients	Chlorhexidine gluconate 1.2 mg/ml, metronidazole 0.2 mg/ml.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	50ml;200ml
Manufacturer	Sinomune Pharmaceutical Co., Ltd.

Chlorhexidine gluconate ointment
Ingredients	Contains 0.2% chlorhexidine gluconate.
Indication	1. This product should not be used with soap, alkali, potassium permanganate and iodine preparations. 2. If used with other drugs at the same time, drug interactions may occur. Please consult a doctor or pharmacist for details.
Specifications	0.002
Manufacturer	Guangdong Cr.shunfeng Pharmaceutical Co., Ltd.

Metronidazole chlorhexidine lotion
Ingredients	Chlorhexidine gluconate 1.2 mg/ml, metronidazole 0.2 mg/ml.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	200ml

See More Related Drugs

Registered Holders

GARONIT PHARMACEUTICALS INC

United States
Active
FAR SPECIALTY PRODUCTS INC DBA FAR CHEMICAL

United States
Active
XTTRIUM LABORATORIES INC

United States
Active

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Guide of Chlorhexidine gluconate

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
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