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Doxycycline hyclate

pharmaceutical raw materials
Doxycycline hyclate structure

Doxycycline hyclate 

structure
  • CAS No:

    24390-14-5

  • Formula:

    C22H24N2O8.1/2C2H6O.ClH.1/2H2O

  • Chemical Name:

    Doxycycline hyclate

  • Synonyms:

    2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,hydrochloride,(4S,4aR,5S,5aR,6R,12aS)-,compd. with ethanol,hydrate (2:2:1:1);2-Naphthacenecarboxamide,4β-(dimethylamino)-1,4,4aβ,5,5aβ,6,11,12a-octahydro-3,5β,10,12,12aβ-pentahydroxy-6β-methyl-1,11-dioxo-,monohydrochloride,compd. with ethyl alc. (2:1),monohydrate;2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,monohydrochloride,[4S-(4α,4aα,5α,5aα,6α,12aα)]-,compd. with ethanol (2:1),monohydrate;2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,monohydrochloride,(4S,4aR,5S,5aR,6R,12aS)-,compd. with ethanol (2:1),monohydrate;Ethanol,compd. with [4S-(4α,4aα,5α,5aα,6α,12aα)]-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride (1:2),monohydrate;Ethanol,compd. with (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride (1:2),monohydrate;Doxycycline hydrochloride hemiethanolate hemihydrate;Doxycycline hyclate;6-Desoxy-5-hydroxytetracycline hydrochloride hemihydrate hemiethanolate;Atridox;Periostat;Monodoks;Tetraclean;BioPure MTAD;62149-53-5;1258072-64-8

  • Categories:

    Active Pharmaceutical Ingredients  >  Antibiotics

Description

Doxycycline (hyclate) is a tetracycline antibiotic and broad-spectrum metalloproteinase (MMP) inhibitor.

Doxycycline hyclate Basic Attributes

1025.87000

1024.31000

2941302000

Characteristics

392.70000

2.24370

yellow crystallien powder

206-209°C (dec.)

685.2ºC at 760 mmHg

368.2ºC

Soluble in water to 50mg/ml. May require warming.Soluble in water, methanol. Sparingly soluble in ethanol. Insoluble in chloroform and ether.

1.03E-19mmHg at 25°C

LD50 i.p. in rats: 262 mg/kg (Goldenthal)

Safety Information

NONH for all modes of transport

3

R22; R36/37/38

S26

QI8925000

Xn

P261-P305 + P351 + P338

H302-H315-H319-H335

Doxycycline hyclate Use and Manufacturing

1. Tetracycline antibiotics group
2. Antibacterial.

Price Analysis

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