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Heparin sodium

Heparin sodium structure

CAS No:
9041-08-1
Chemical Name:
Heparin sodium
Synonyms:
Heparin,sodium salt;Heparin sodium;Sodium acid heparin;Sodium heparin;Depo-Heparin;Hed-Heparin;Hepathrom;Sodium heparinate;Pularin;Liquemin;Liquaemin sodium;Alfa 87-81;Alfa 88-247;Alfa 87-120;Alfa 87-163;Alfa 87-198;Reviparin sodium;Dalteparin sodium;Parnaparin sodium;Tinzaparin sodium;Kabi 2165;Fragmin;LHN 1;Logiparin;Inno-Hep;Fragmin IV;Ardeparin sodium;WY 90493RD;Normiflo;RP 54563;Minolteparin sodium;RO 11;Bemiparin sodium;H 2149;Lioton 1000;OP 2000;Deligoparin sodium;Hepalean;Panheprin;Thromboliquine;Minihep;Lipo-Hepinette;Thrombo-Hepin;Heparin Fragment Kabi 2165;Unihep;Monoparin;Hepsal;Longheparin;Heprinar;Lipo-Hepin;Sodium parnaparin;Ivor;Zibor;Badyket;Nadroparine sodium;Clivarin 1750;Hepaflush;Hepagumin;Viatromb;Semuloparin sodium;Heparine Choay;Adomiparin sodium;M 118 sodium;RO 14;Sevuparin sodium;Necuparanib sodium;M 402 sodium salt;Clivarina;101921-26-0;102785-31-9;12656-11-0;913079-23-9
Categories:
Cosmetic Ingredient > Skin Conditioning

Description

Heparin sodium salt is an anticoagulant which binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa.

Heparin sodium Basic Attributes

EC Number：

232-681-7

HScode：

30019010

Characteristics

Appearance：

white crystalline (fine)

Water Solubility：

soluble in water, dimethyl sulfoxide and ethanol.H2O: 50 mg/mL, clear, faintly yellow

Storage Conditions：

2-8°C

Toxicity：

LD50 oral in rat: > 779000iu/kg

Specific rotation：

D25 +47° (c = 1.5 in water)

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36/37/38-42/43

safety instructions：

22-24-26-36/37

RTECS Number：

MI0850000

Stability/Shelf Life：

Stable. Incompatible with strong oxidizing agents, strong bases.

Heparin sodium Use and Manufacturing

corrosive moisture sensitive Biochemical research to prevent the conversion of prothrombin into thrombin. Used to delay and prevent blood coagulation production method The intestinal mucosa of pigs, sheep, cattle and other animals is extracted and refined.

Drug Function and Efficacy

No specific description provided

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Dalteparin Sodium Injection
Specifications	0.3ml:7500IU

Heparin Sodium
Manufacturer	Ningbo Renjian Pharmaceutical Group Co., Ltd.

Heparin Sodium Injection
Ingredients	The main ingredients of this product are: heparin sodium. Heparin sodium is a sodium salt of aminoglucosan sulfate extracted and refined from pig intestinal mucosa or cow lung. It belongs to mucopolysaccharide substances. The average molecular weight is 12000.
Indication	1. The use of this product in combination with the following drugs may increase the risk of bleeding: ① Coumarin and its derivatives can lead to severe factor IX deficiency and cause bleeding; ② Aspirin and non-steroidal anti-inflammatory analgesics, including mefenamic acid and salicylic acid, can inhibit platelet function and induce gastrointestinal ulcer bleeding; ③ Dipyridamole and dextran may inhibit platelet function; ④ Adrenocortical hormone, adrenocorticotropic hormone, etc. are prone to induce gastrointestinal ulcer bleeding; ⑤ Other drugs such as diuronic acid, tissue plasminogen activator (t-PA), urokinase, and streptokinase. 2. Heparin combined with sodium bicarbonate, sodium lactate and other drugs to correct acidosis can promote the anticoagulant effect of heparin; 3. Heparin mixed with hyaluronidase injection can not only reduce intramuscular injection pain, but also promote heparin absorption. However, heparin can inhibit the activity of hyaluronidase, so the two should be used temporarily in combination, and the drugs should not be left for a long time after mixing; 4. Heparin can interact with insulin receptors, thereby changing the binding and action of insulin. There have been reports of heparin-induced hypoglycemia; 5. The following drugs are incompatible with this product: kanamycin, amikacin, daunorubicin, erythromycin lactobionate, gentamicin sulfate, hydrocortisone sodium succinate, polymyxin B, doxorubicin, tobramycin, vancomycin, cefoperazone, cefoperazone, cephalothin sodium, chloroquine, promethazine, and narcotic analgesics.
Specifications	2ml:5000 units
Manufacturer	Ma'anshan Fengyuan Pharmaceutical Co., Ltd.

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Registered Holders

BIOIBERICA SAU

United States
Active
EMCURE PHARMACEUTICALS LTD

United States
Active
INTERNATIONAL MEDICATION SYSTEMS LTD

United States
Active

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