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Melittin

Melittin structure

Melittin 

structure

Description

solid


Basic polypeptide from the venom of the honey bee (Apis mellifera). It contains 26 amino acids, has cytolytic properties, causes contracture of muscle, releases histamine, and disrupts surface tension, probably due to lysis of cell and mitochondrial membranes.

Melittin Basic Attributes

2846.46

2845.757527

253-417-7

Characteristics

1150

112 °C

2-8°C

613.8 Ų [M+2H]2+

Safety Information

UN 3462 6.1/PG 1

3

23/24/25-21/22

36

OS3965000

T,Xn

Stable. Incompatible with strong oxidizing agents.

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P280, P301+P312, P302+P352, P312, P322, P330, P363, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Melitten

Melittin Use and Manufacturing

Antirheumatic drug.

Computed Properties

Molecular Weight:2846.5
XLogP3:-2.7
Hydrogen Bond Donor Count:41
Hydrogen Bond Acceptor Count:37
Rotatable Bond Count:99
Exact Mass:2845.7575265
Monoisotopic Mass:2844.7541717
Topological Polar Surface Area:1150
Heavy Atom Count:201
Complexity:6300
Undefined Atom Stereocenter Count:28
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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