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Polysucrose

Polysucrose structure

CAS No:
26873-85-8
Formula:
(C12H22O11.C3H5ClO)x
Chemical Name:
Polysucrose
Synonyms:
FICOLL-400(TM);FICOLL(R) 400;FICOLL(R) 400000;FICOLL(R) 400 REAGENT;FICOLL(R) PM 400;FICOLL(R);POLYSUCROSE;POLYSUCROSE 400
Categories:
Organic Chemistry > Alcohols, Phenols, Phenol Alcohols

Description

Polysucrose (sold as FicollTM by GE Healthcare) is a high molecular weight polymer formed by the copolymerization of sucrose with epichlorohydrin. It is used for cell separation and organelle isolation, in the study to develop a new method for the purification of human motile spermatozoa, and in the investigation of antiproliferative and antitumor activities of D-reverse peptides.

pH 7.0-8.0

Ficoll 400 is a highly branched polymer formed by the copolymerization of sucrose and epichlorohydrin. Ficoll 400 is completely non-ionic. Because of the abundance of hydroxyl groups, Ficoll 400 is very hydrophilic and extremely water-soluble. The most common application for Ficoll 400 is as a density gradient medium for the separation and isolation of eukaryotic cells, organelles and bacterial cells. Density ranges up to 1.2 g/ml can be attained. It has also been utilized in a variety of other applications.

Polysucrose Basic Attributes

Molecular Weight：

434.82

EC Number：

608-012-3

TSCA：

TSCA listed

Color/Form：

White

HScode：

39072090

Characteristics

Density：

1.055-1.075g/mL

Water Solubility：

Soluble in water.

Critical Temperature & Pressure：

room temp

Safety Information

wgk germany：

hazard class code：

safety instructions：

26-36

Polysucrose Use and Manufacturing

Used for cell separation and organelle isolation. Polysucrose has been used in a study to develop a new method for the purification of human motile spermatozoa. It has also been used in a study that investigated the antiproliferative and antitumor activities of D-reverse peptides.

Polysucrose has been used in a study to develop a new method for the purification of human motile spermatozoa. It has also been used in a study that investigated the antiproliferative and antitumor activities of D-reverse peptides.

Ficoll is a hydrophilic neutral highly branched polysaccharide use to establish density gradients to separate blood component cells and organelles. It is part of the separation medium called Ficoll-Paque.

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