N-Didesmethylsibutramine
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N-Didesmethylsibutramine
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CAS No:
84467-54-9
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Formula:
C15H22ClN
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Chemical Name:
N-Didesmethylsibutramine
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Synonyms:
Cyclobutanemethanamine,1-(4-chlorophenyl)-α-(2-methylpropyl)-;1-(4-Chlorophenyl)-α-(2-methylpropyl)cyclobutanemethanamine;N-Didemethylsibutramine;(±)-Didesmethylsibutramine;1-[1-(4-Chlorophenyl)cyclobutyl]-3-methylbutylamine;N-Didesmethylsibutramine;1-[1-(4-Chlorophenyl)cyclobutyl]-3-methylbutan-1-amine
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CAS No:
Drug Information
Agents that are used to suppress appetite. (See all compounds classified as Appetite Depressants.)|Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. (See all compounds classified as Antidepressive Agents.)
1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutylamine is a known human metabolite of Desmethylsibutramine, (S)-.
(R)-DDMS
N-Didesmethylsibutramine Use and Manufacturing
A metabolite of Sibutramine, a serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure
Computed Properties
Molecular Weight:251.79
XLogP3:4.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:251.1440774
Monoisotopic Mass:251.1440774
Topological Polar Surface Area:26
Heavy Atom Count:17
Complexity:239
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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