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Etripamil

Etripamil structure

CAS No:
853400-76-7
Formula:
C13H21N3O6
Chemical Name:
Etripamil
Synonyms:
Trofinetide(NNZ2566);TROFINETIDE; NNZ2566 ;NNZ 2566; NNZ-2566;Etripamil;NNZ-2566;L-Glutamic acid, glycyl-2-methyl-L-prolyl-
Categories:
Organic Chemistry > Hydrocarbons and Derivatives

Description

Trofinetide (NNZ-2566), a neuroprotective analogue of [glypromate], is a novel molecule that has a profile suitable for both intravenous infusion and chronic oral delivery. It is currently in development to treat traumatic brain injury.

Etripamil Basic Attributes

Molecular Weight：

315.32

Exact Mass：

315.14303540

UNII：

Z2ME8F52QL

Characteristics

Density：

1.377±0.06 g/cm3

Melting Point：

144 °C

Boiling Point：

655.4±55.0 °C(Predicted)

PKA：

3.51±0.10

Drug Information

Drug Indication：

Investigated for use/treatment in traumatic brain injuries.

Pharmacology：

NNZ-2566 is shown to have multi-faceted action to significantly reduce both inflammation and apoptosis (cell death), protecting the neurons and their surrounding infrastructure.

MeSH Entry Terms：

glycyl-l-2-methylprolyl-l-glutamic acid

Etripamil Use and Manufacturing

Use Classification：

Human drugs -> Rare disease (orphan)

Computed Properties

Molecular Weight:315.32
XLogP3:-3.9
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:7
Exact Mass:315.14303540
Monoisotopic Mass:315.14303540
Topological Polar Surface Area:150
Heavy Atom Count:22
Complexity:480
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Etripamil

Shaanxi Dideu Medichem Co. Ltd Contact Supplier

CN
4 YRS

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Etripamil

CAS No.: 853400-76-7

Content: 98%

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Tianjin Jinshu Technology Co., Ltd. Contact Supplier

CN
3 YRS

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Trader Supplier of peptone

High quality Trofinetide CAS NO.853400-76-7 human with Safe Delivery

CAS No.: 853400-76-7

Grade: Industrial Grade

Content: 99%

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