Nimbolide
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Nimbolide
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CAS No:
25990-37-8
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Formula:
C27H30O7
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Chemical Name:
Nimbolide
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Synonyms:
2H,5H-Cyclopenta[d′]naphtho[1,8-bc:2,3-b′]difuran-6-acetic acid,8-(3-furanyl)-2a,5a,6,6a,8,9,9a,10a,10b,10c-decahydro-2a,5a,6a,7-tetramethyl-2,5-dioxo-,methyl ester,(2aR,5aR,6S,6aR,8R,9aR,10aS,10bR,10cR)-;2H,5H-Cyclopenta[d′]naphtho[1,8-bc:2,3-b′]difuran-6-acetic acid,8α-(3-furyl)-2a,5a,6,6a,8,9,9a,10a,10b,10c-decahydro-2a,5a,6a,7-tetramethyl-2,5-dioxo-,methyl ester;18,24-Dinor-11,12-secochola-2,13,20,22-tetraene-4,11-dicarboxylic acid,7,15:21,23-diepoxy-6-hydroxy-4,8-dimethyl-1-oxo-,γ-lactone,methyl ester,(4α,5α,6α,7α,15β,17α)-;2H,5H-Cyclopenta[d′]naphtho[1,8-bc:2,3-b′]difuran,18,24-dinor-11,12-secochola-2,13,20,22-tetraene-4,11-dicarboxylic acid deriv.;Nimbolide;NSC 309909
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CAS No:
Nimbolide Use and Manufacturing
Nimbolide, a natural triterpenoid present in the edible parts of the neem tree (Azadirachta indica), was found to be growth-inhibitory in human colon carcinoma HT-29 cells. Nimbolide treatment of cells at 2.5 - 10 μM resulted in moderate to very strong gr
Computed Properties
Molecular Weight:466.5
XLogP3:2.2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:466.19915329
Monoisotopic Mass:466.19915329
Topological Polar Surface Area:92
Heavy Atom Count:34
Complexity:1040
Undefined Atom Stereocenter Count:9
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes