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Home > Encyclopedia > 1-METHYL-1H-INDAZOL-5-AMINE

1-METHYL-1H-INDAZOL-5-AMINE

1-METHYL-1H-INDAZOL-5-AMINE structure

1-METHYL-1H-INDAZOL-5-AMINE 

structure
  • CAS No:

    50593-24-3

  • Formula:

    C8H9N3

  • Chemical Name:

    1-METHYL-1H-INDAZOL-5-AMINE

  • Synonyms:

    1-methyl-5-indazolamine;1-methyl-1H-indazole-5-amine;1H-Indazol-5-amine, 1-methyl-;1-methyl-1H-indazol-5-amine(SALTDATA: FREE);5-AMino-1-Methyl-1H-indaz...;5-aMino-1-Methylindazole;1-METHYL-1H-INDAZOL-5-AMINE;1-METHYL-1H-INDAZOL-5-YLAMINE

1-METHYL-1H-INDAZOL-5-AMINE Basic Attributes

147.18

147.079647300

DTXSID70377635

2933990090

Characteristics

43.84000

1.73670

1.27±0.1 g/cm3

142-144°C

321.6±15.0 °C(Predicted)

148.3ºC

1.667

3.85±0.10

Safety Information

IRRITANT

Xi

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

1-METHYL-1H-INDAZOL-5-AMINE Use and Manufacturing

1-Methyl-5-amino-1H-indazole is used in preparation of Hydrazone compounds having (Hetero)aryl group at terminal Amine group for treating tau protein-associated disease. Also, used in preparation of Dihydroisoindole-1H-pyrazolo[3,4-d]pyrimidinone compounds as Wee1 inhibitors for treatment of kinase-related diseases.

Computed Properties

Molecular Weight:147.18
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Exact Mass:147.079647300
Monoisotopic Mass:147.079647300
Topological Polar Surface Area:43.8
Heavy Atom Count:11
Complexity:148
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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