Product
Supplier
Encyclopedia
Inquiry
Home > Encyclopedia > (+)-Propranolol hydrochloride

(+)-Propranolol hydrochloride

(+)-Propranolol hydrochloride structure

(+)-Propranolol hydrochloride 

structure
  • CAS No:

    13071-11-9

  • Formula:

    C16H21NO2.ClH

  • Chemical Name:

    (+)-Propranolol hydrochloride

  • Synonyms:

    2-Propanol,1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-,hydrochloride (1:1),(2R)-;2-Propanol,1-(isopropylamino)-3-(1-naphthyloxy)-,hydrochloride,(+)-;2-Propanol,1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-,hydrochloride,(R)-;2-Propanol,1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-,hydrochloride,(2R)-;(+)-Propranolol hydrochloride;d-Propranolol hydrochloride;(+)-1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride;Dexpropranolol hydrochloride;AY 20694;R-(+)-1-Isopropylamino-3-(1-naphthoxy)-2-propanol hydrochloride;ICI 47319;d-Anapriline;(R)-(+)-Propranolol hydrochloride;(R)-Propranolol hydrochloride;(+)-Anapriline;(R)-1-(Isopropylamino)-3-(naphthalen-1-yloxy)propan-2-ol hydrochloride

  • Categories:

    Organic Chemistry  >  Amides

Description

A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.

(+)-Propranolol hydrochloride Basic Attributes

295.80400

295.1339066 g/mol

235-961-7

AB9DB0NX46

2922509090

Characteristics

41.49000

3.77040

192 °C @ Solvent: Isopropanol

434.9ºC at 760 mmHg

216.8ºC

2-8ºC

2.48E-08mmHg at 25°C

161.4 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Safety Information

3

R22

S22-S24/25

Xn

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 41 companies from 2 notifications to the ECHA C&L Inventory.

Drug Information

Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)|Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)|Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety. (See all compounds classified as Adrenergic beta-Antagonists.)|Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)

Anaprilin

Computed Properties

Molecular Weight:295.80
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:295.1339066
Monoisotopic Mass:295.1339066
Topological Polar Surface Area:41.5
Heavy Atom Count:20
Complexity:257
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Recommended Suppliers of (+)-Propranolol hydrochloride

Scan the QR Code to Share

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.