 Home > Encyclopedia > Hoechst 33258

Hoechst 33258

Hoechst 33258 structure

CAS No:
23491-45-4
Formula:
C25H24N6O.3ClH
Chemical Name:
Hoechst 33258
Synonyms:
Phenol,4-[6-(4-methyl-1-piperazinyl)[2,6′-bi-1H-benzimidazol]-2′-yl]-,hydrochloride (1:3);Phenol,p-[5-[5-(4-methyl-1-piperazinyl)-2-benzimidazolyl]-2-benzimidazolyl]-,trihydrochloride;Phenol,4-[5-(4-methyl-1-piperazinyl)[2,5′-bi-1H-benzimidazol]-2′-yl]-,trihydrochloride;2-[2-(4-Hydroxyphenyl)-6-benzimidazolyl]-6-(1-methyl-4-piperazinyl)benzimidazole trihydrochloride;2-[2-(4-Hydroxyphenyl)-6-benzimidazolyl]-6-(1-methyl-4-piperazyl)benzimidazole-3HCl;2-[2-(4-Hydroxyphenyl)-6-benzimidazolyl]-6-(1-methyl-4-piperazyl)benzimidazole trichloride;2-[2-(4-Hydroxyphenyl)-6-benzimidazolyl]-6-(1-methyl-4-piperazyl)-benzimidazole trihydrochloride;Hoechst 33258;HOE 33258;H 33258;Bisbenzimide;4-[5-[5-(4-Methyl-1-piperazinyl)-2-benzimidazolyl]-2-benzimidazolyl]phenol trihydrochloride;Bisbenzimide (quenchant);Bisbenzimide trihydrochloride;2′-(4-Hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5′-bi-1H-benzimidazole;Ho 33258;NSC 322921;Pibenzimol hydrochloride;Bisbenzimide H 33258;53025-60-8;91932-18-2;93038-90-5;863126-37-8
Categories:
Dyes and Pigments > Dye

Description

A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.

Hoechst 33258 Basic Attributes

Molecular Weight：

533.88000

Exact Mass：

532.131193 g/mol

NSC Number：

322921

Characteristics

PSA：

84.07000

XLogP3：

6.63950

Appearance：

yellow-green powder.

Melting Point：

314ºC

Boiling Point：

643.1ºC

Flash Point：

342.7ºC

Water Solubility：

soluble

Storage Conditions：

2-8ºC

Safety Information

wgk germany：

hazard class code：

R22

safety instructions：

26-36-24/25-23

RTECS Number：

SM1140500

Marks：

Stability/Shelf Life：

Stable under normal temperatures and pressures.

Precautionary statement(s)：

P305 + P351 + P338

Hazard Statements：

H302; H315; H319

Drug Information

MeSH：

Chemicals that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags. (See all compounds classified as Fluorescent Dyes.)|Pharmacological agents destructive to nematodes in the superfamily Filarioidea. (See all compounds classified as Filaricides.)

MeSH Entry Terms：

4-(5-(4-Methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)phenol, trihydrochloride

Computed Properties

Molecular Weight:461.0
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:460.1778371
Monoisotopic Mass:460.1778371
Topological Polar Surface Area:84.1
Heavy Atom Count:33
Complexity:634
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Recommended Suppliers of Hoechst 33258

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

Hoechst 33258

CAS No.: 23491-45-4

Content: 99.00%

Inquiry