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Ecopipam

Ecopipam structure

Ecopipam 

structure
  • CAS No:

    112108-01-7

  • Formula:

    C19H20ClNO

  • Chemical Name:

    Ecopipam

  • Synonyms:

    5H-Benzo[d]naphth[2,1-b]azepin-12-ol,11-chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-,(6aS,13bR)-;5H-Benzo[d]naphth[2,1-b]azepin-12-ol,11-chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-,(6aS-trans)-;(6aS,13bR)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo[d]naphth[2,1-b]azepin-12-ol;Ecopipam;SCH 39166;PSYRX 101

Description

(6aS,13bR)-11-chloro-7-methyl-5,6,6a,8,9,13b-hexahydronaphtho[1,2-a][3]benzazepin-12-ol is a benzazepine.|Ecopipam has been used in trials studying the treatment of Tourette's Syndrome, Lesch-Nyhan Disease, Pathological Gambling, and Self-injurious Behavior.

Ecopipam Basic Attributes

313.8 g/mol

313.82

0X748O646K

DTXSID8043814

Characteristics

23.5 Ų

Drug Information

Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus. (See all compounds classified as Antipsychotic Agents.)|Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME. (See all compounds classified as Dopamine Antagonists.)

6,7,7a,8,9,13b-hexahydro-3-chloro-2-hydroxy-N-methyl-5H-benzo(d)naphtho-(2,1b)azepine

Ecopipam Use and Manufacturing

Human drugs -> Rare disease (orphan)

Computed Properties

Molecular Weight:313.8
XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Exact Mass:313.1233420
Monoisotopic Mass:313.1233420
Topological Polar Surface Area:23.5
Heavy Atom Count:22
Complexity:403
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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