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Roxindole

Roxindole structure

Roxindole 

structure
  • CAS No:

    112192-04-8

  • Formula:

    C23H26N2O

  • Chemical Name:

    Roxindole

  • Synonyms:

    1H-Indol-5-ol,3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-;3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indol-5-ol;Roxindole

Description

Roxindole is a member of indoles. It has a role as an alpha-adrenergic antagonist and a serotonergic drug.

Roxindole Basic Attributes

346.5 g/mol

346.47

43227SMS0O

DTXSID5043895

Characteristics

39.3 Ų

Drug Information

Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. (See all compounds classified as Antidepressive Agents.)|Drugs that bind to and activate dopamine receptors. (See all compounds classified as Dopamine Agonists.)

3-(4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-1H-indol-5-ol

Computed Properties

Molecular Weight:346.5
XLogP3:4.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:346.204513457
Monoisotopic Mass:346.204513457
Topological Polar Surface Area:39.3
Heavy Atom Count:26
Complexity:471
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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