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Extinguish

Extinguish structure

Extinguish 

structure
  • CAS No:

    65733-16-6

  • Formula:

    C19H34O3

  • Chemical Name:

    Extinguish

  • Synonyms:

    2,4-Dodecadienoic acid,11-methoxy-3,7,11-trimethyl-,1-methylethyl ester,(2E,4E,7S)-;2,4-Dodecadienoic acid,11-methoxy-3,7,11-trimethyl-,1-methylethyl ester,[S-(E,E)]-;d-Methoprene;ZR 2458;(7S)-Methoprene;(+)-Methoprene;S-Methoprene;Extinguish;Altoside CP 10;Altoside CP 2;Altosid XR Briquets;Diacon II;Precor

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

(S)-methoprene is a methoprene. It is an enantiomer of a (R)-methoprene.

Extinguish Basic Attributes

310.5 g/mol

310.47

613-834-0

4YIQ0A94UR

758655

DTXSID1035783

QP54AA54|QP53AX65

Characteristics

35.5 Ų

187 Ų [M+Na]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Safety Information

|Warning|H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]|P273, P391, and P501|H315 (20%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P273, P280, P302+P352, P304+P340, P312, P321, P332+P313, P362, P391, P403+P233, P405, and P501|Aggregated GHS information provided by 5 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

Drug Information

For cats with, or at risk from mixed infestations by cestodes, nematodes and ectoparasites. The veterinary medicinal product is exclusively indicated when all three groups are targeted at the same time.EctoparasitesTreatment and prevention of infestations by fleas (Ctenocephalides felis). Elimination of fleas within 24 hours. One treatment prevents further infestations for at least one month.Prevention of environmental flea contamination by inhibiting the development of flea immature stages (eggs, larvae and pupae) for over a month.The product can be used as part of a treatment strategy for the control of flea allergy dermatitis (FAD).Treatment and prevention of infestations by ticks (Ixodes ricinus). Elimination of ticks within 48 hours. One treatment prevents further infestations for up to 3 weeks.Treatment of notoedric mange (Notoedres cati).CestodesTreatment of infestations with tapeworms (Dipylidium caninum, Taenia taeniaeformis, Echinococcus multilocularis, Joyeuxiella pasqualei (adult), and Joyeuxiella fuhrmanni (adult)).NematodesTreatment of infestations with gastrointestinal nematodes (L3, L4 larvae and adults of Toxocara cati, adults of Toxascaris leonina, L4 larvae and adults of Ancylostoma tubaeforme and Ancylostoma ceylanicum, and adults of Ancylostoma brazilienze).Treatment of infestations with feline lungworms (L3 larvae, L4 larvae and adults of Aelurostrongylus abstrusus, L4 larvae and adults of Troglostrongylus brevior).Treatment of infestations with vesical worms (Capillaria plica).Prevention of heartworm disease (Dirofilaria immitis larvae) for one month.|Treatment and prevention of infestations in dogs by ticks (Ixodes ricinus, Dermacentor reticulatus, Rhipicephalus sanguineus, Ixodes scapularis, Dermacentor variabilis, Haemaphysalis elliptica, Haemaphysalis longicornis, Amblyomma americanum and Amblyomma maculatum) and fleas (Ctenocephalides felis and Ctenocephalides canis). Treatment of infestations by chewing lice (Trichodectes canis). Prevention of environmental flea contamination by inhibiting the development of all flea immature stages. The product can be used as part of a treatment strategy for the control of flea-allergy dermatitis. Elimination of fleas and ticks within 24 hours. One treatment prevents further infestations for five weeks by ticks and for up to five weeks by fleas.The treatment indirectly reduces the risk of transmission of tick-borne diseases (canine babesiosis, monocytic ehrlichiosis, granulocytic anaplasmosis and borreliosis) from infected ticks for four weeks.

Extinguish Use and Manufacturing

Veterinary drugs -> Broadline -> EMA Drug Category|Avermectins, Eprinomectin, combinations, Antiparasitic products, insecticides and repellents -> Veterinary pharmacotherapeutic group|Veterinary drugs -> Certifect -> EMA Drug Category|Ectoparasiticides for topical use, incl. insecticides -> Veterinary pharmacotherapeutic group

Computed Properties

Molecular Weight:310.5
XLogP3:5.5
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:11
Exact Mass:310.25079494
Monoisotopic Mass:310.25079494
Topological Polar Surface Area:35.5
Heavy Atom Count:22
Complexity:378
Defined Atom Stereocenter Count:1
Defined Bond Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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