1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
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1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
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CAS No:
18194-24-6
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Formula:
C36H72NO8P
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Chemical Name:
1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
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Synonyms:
(R)-(7-myristoyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphatricosyl)trimethylammonium 4-oxide;1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;1,2-Ditetradecanoyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-dimyristoyl, L-β,γ-Dimyristoyl-α-lecithin;[O-(1-O,2-O-Dimyristoyl-L-glycero-3-phospho)choline]anion;1,2-Dimyristoyl-L-3-phosphatidylcholine;sn-3-Dimyristoyllecithin;β,γ-Dimyristoyl-L-α-phosphatidylcholine;L-β,γ-Dimyristoyl-α-lecithin
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CAS No:
Description
1,2-Dimyristoyl-sn-glycero-3-PC (DMPC) is a phospholipid containing 14:0 fatty acids at thesn-1 andsn-2 positions. It is a synthetic phosopholipid that has been used for liposome production in order to study the properties of lipid bilayer.
white powder
ChEBI: A 1,2-diacyl-sn-glycero-3-phosphocholine where the two phosphatidyl acyl groups are specified as tetradecanoyl (myristoyl).
1,2-dimyristoyl-sn-glycero-3-phosphocholine is a synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes.
It has three forms 1, 2 and '. Recrystallise it from aqueous EtOH or EtOH/Et2O. Its solubility at 22-23o in Et2O is 0.03%, in Me2CO it is 0.06% and in pyridine it is 1.3%. [Baer & Kates J Am Chem Soc 72 942 1950, Baer & Maurakas J Am Chem Soc 74 158 1952, IR: Marinetti & Stotz J Am Chem Soc 76 1347 1954.] The S-isomer with 1H2O is recrystallised from 2,6-dimethylheptan-4-one and has m 226-227o (sintering at 90-95o), and [] 20D -7o (c 6, MeOH/CHCl3 1:1). [Baer & Martin J Biol Chem 193 835 1951, Beilstein 4 IV 1463.]
1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Basic Attributes
677.93
3921768
242-085-9
White to Off-White
29232000
1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Use and Manufacturing
1,2-dimyristoyl-sn-glycero-3-phosphocholine is a phospholipid containing 14:0 fatty acids at the sn-1 and sn-2 positions. It is a synthetic phosopholipid that can be used for liposome production in order to study the properties of lipid bilayer.[Cayman Chemical]
1,2-Dimyristoyl-sn-glycero-3-phosphocholine has been used as a standard for phospholipid analysis by LC-ESI-MS.
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