Gamma oryzanol
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Gamma oryzanol
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CAS No:
11042-64-1
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Formula:
C40H58O4
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Chemical Name:
Gamma oryzanol
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Synonyms:
GAMMA-ORYZANOL;.gamma.-Orizanol;gamma-orizanol;gamma-oz;gammariza;Major coMpounds: Cycloartenylferulate and 24-Methylen Cycloartanylferulate;Other coMpounds: CaMpesterylferulate, CaMpestanylferulate, β-Sitosterylferulate and Cycloartanylferulate;Gu Weisu
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CAS No:
Description
Gamma oryzanol is a lipid fraction derived from rice-bran oil. Oryzanol was first isolated from rice-bran oil in the 1950s. Several lipid fractions were isolated from the oil.The third (gamma) fraction isolated was oryzanol.It is made up of a mixture of ferulic acid esters and plant sterols. Similar in structure to cholesterol, the phytosterols and triterpenes that comprise oryzanol include campesterol, stigmasterol, beta sitosterol, cycloartanol, and cycloartenol. Because phytosterols are poorly absorbed, it has been suggested that they may reduce blood cholesterol by inhibiting intestinal cholesterol absorption.In contrast, the ferulic acid portion of gamma oryzanol is easily absorbed into the body's tissues. Ferulic acid also has demonstrated antioxidant properties in vitro.
White to Off-White Solid
ChEBI: Gamma-Oryzanol (TN) is a triterpenoid.
Gamma oryzanol is found in the by-products of the rice industry, such as rice bran and rice bran oil. It exhibits a wide range of biological activities, including anticarcinogenic, anti-inflammatory, antihyperlipidemic, and neuroprotective properties, which are primarily due to its high antioxidant capacity.
A poison by skin contact. Moderately toxic by intravenous route. Low toxicity by ingestion. Experimental reproductive effects. When heated to decompositionit emits acrid smoke and irritating vapors.
Characteristics
0.9751 (rough estimate)
135-137°C
571.92°C (rough estimate)
1.4760 (estimate)
Practically insoluble in water
LD50 oral in rat: > 25gm/kg
little or no odor
Sealed in dry,Room Temperature
Gamma oryzanol Use and Manufacturing
Gamma Oryzanol is a mixture of 6 substances derived from rice bran oil, including sterols and ferulic acid, called Cycloartanyl Ferulate or Triterpene alcohol ferulate. It has been approved in Japan for several conditions, including menopausal symptoms, mild anxiety, stomach upset, and high cholesterol. In the US, it is widely used as a sports supplement, as well as for reducing cholesterol. gamma oryzanol is widely used as a food additive, pharmaceutical material. In cosmetic area, the application to creams and sunscreens exploiting its skin age resistor function and ultraviolet absorbing effect.
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