Product
Supplier
Encyclopedia
Inquiry
Home > Encyclopedia > Octocrylene

Octocrylene

pharmaceutical raw materials
Octocrylene structure

Octocrylene 

structure
  • CAS No:

    6197-30-4

  • Formula:

    C24H27NO2

  • Chemical Name:

    Octocrylene

  • Synonyms:

    2-Propenoic acid,2-cyano-3,3-diphenyl-,2-ethylhexyl ester;Acrylic acid,2-cyano-3,3-diphenyl-,2-ethylhexyl ester;Agent AT 539;Uvinul N 539;2-Ethylhexyl 2-cyano-3,3-diphenylacrylate;2-Ethylhexyl α-cyano-β-phenylcinnamate;Octocrylene;2-Ethylhexyl 2-cyano-3,3-diphenyl-2-propenoate;Octocrilene;2′-Ethylhexyl 2-cyano-3-phenylcinnamate;Viosorb 930;2-Ethylhexyl α-cyano-β,β′-diphenylacrylate;Uvinul 3039;Eusolex OCR;Sanduvor 3039;Neo Heliopan 303;Uvinul N 539T;Uvinul N 539SG;2-Cyano-3,3-diphenylacrylic acid 2-ethylhexyl ester;CA 1 (light stabilizer);CA 1;Parsol 340;Seesorb 502;Escalol 597;2-Ethylhexyl-3,3-diphenylcyanoacrylate;N 539;UV 3039;80135-31-5;149984-83-8;194304-33-1

  • Categories:

    Cosmetic Ingredient  >  Light Stabilizer

Description

Octocrylene is an organic compound used as an ingredient in sunscreens and cosmetics.


2-ethylhexyl-2-cyano-3,3-diphenylacrylate is a yellow viscous liquid. Insoluble in water. (NTP, 1992)|Liquid


2-ethylhexyl-2-cyano-3,3-diphenylacrylate is a yellow viscous liquid. Insoluble in water. (NTP, 1992)|Octocrylene is a diarylmethane.

Octocrylene Basic Attributes

361.48

361.48

228-250-8

DTXSID9025299

29269095

Characteristics

50.1

7.1

2-ethylhexyl-2-cyano-3,3-diphenylacrylate is a yellow viscous liquid. Insoluble in water. (NTP, 1992)

1.1±0.1 g/cm3

−10 °C(lit.)

218 °C1.5 mm Hg(lit.)

>230 °F

1.546

Insoluble (NTP, 1992)

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

LD50 orl-rat: >5 g/kg NTIS** OTS0556792

Insoluble in water.

Nitriles

Polymerizable

2-ETHYLHEXYL-2-CYANO-3,3-DIPHENYLACRYLATE is an acrylate ester derivative. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Safety Information

NONH for all modes of transport

1

52

29/56

UD3328750

P273, P501

H413

Flash point data for this chemical are not available. It is probably combustible. (NTP, 1992)

|Warning|H410 (22.46%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]|P273, P391, and P501|Aggregated GHS information provided by 626 companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

This compound is not very flammable but any fire involving this compound may produce dangerous vapors. You should evacuate the area. All firefighters should wear full-body protective clothing and use self-contained breathing apparatuses. You should extinguish any fires involving this chemical with a dry chemical, carbon dioxide, foam, or halon extinguisher. (NTP, 1992)

SMALL SPILLS AND LEAKAGE: If you spill this chemical, use absorbent paper to pick up liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with toluene followed by washing with a strong soap and water solution. Do no reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this material in a refrigerator. (NTP, 1992)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

Drug Information

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

2-ethylhexyl 2-cyano-3,3-diphenyl-2-propenoate

Octocrylene Use and Manufacturing

Uses

Octrelin is a UV-A and UV-B filter used in sunscreen and topical pharmaceutical formulations. Used as UV absorber for plastics, coatings, dyes, etc.


Intermediates


Personal care products

Production

500,000 - 1,000,000 lb

All other chemical product and preparation manufacturing|2-Propenoic acid, 2-cyano-3,3-diphenyl-, 2-ethylhexyl ester: ACTIVE

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients|Cosmetics -> Uv absorber; Uv filter

Computed Properties

Molecular Weight:361.5
XLogP3:7.1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:10
Exact Mass:361.204179104
Monoisotopic Mass:361.204179104
Topological Polar Surface Area:50.1
Heavy Atom Count:27
Complexity:510
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Provides protection from UVB rays and helps stabilize other sunscreen agents like Avobenzone.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Registered Holders

  • GALAXY SURFACTANTS LTD

    India India
    Inactive

Recommended Suppliers of Octocrylene

Scan the QR Code to Share

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.