 Home > Encyclopedia > (+)-Cucurbitacin B

(+)-Cucurbitacin B

(+)-Cucurbitacin B structure

CAS No:
6199-67-3
Formula:
C32H46O8
Chemical Name:
(+)-Cucurbitacin B
Synonyms:
19-Norlanosta-5,23-diene-3,11,22-trione,25-(acetyloxy)-2,16,20-trihydroxy-9-methyl-,(2β,9β,10α,16α,23E)-;19-Nor-9β,10α-lanosta-5,23-diene-3,11,22-trione,2β,16α,20,25-tetrahydroxy-9-methyl-,25-acetate;(2β,9β,10α,16α,23E)-25-(Acetyloxy)-2,16,20-trihydroxy-9-methyl-19-norlanosta-5,23-diene-3,11,22-trione;Cucurbitacin B;Cucurbitacine B;Amarine;NSC 144154;NSC 49451;(+)-Cucurbitacin B;HY-N 0416;120614-91-7;22076-50-2
Categories:
Biochemical Engineering > Chinese Herbs

Description

Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids; could repress cancer cell progression.IC50 value:Target: anticancer natural compoundin vitro: Cucurbitacin-B inhibited growth and modulated expression of cell-cycle regulators in SHSY5Y cells. At the molecular level, we found that Cucurbitacin-B inhibited AKT signaling activation through up-regulation of PTEN [1]. CuB induced apoptosis of A549 cells in a -concentration-dependent manner, as determined by fluor

(+)-Cucurbitacin B Basic Attributes

Molecular Weight：

558.7

Exact Mass：

558.70

HScode：

29153900

Characteristics

PSA：

138

XLogP3：

2.6

Appearance：

white to beige

Density：

1.2±0.1 g/cm3

Melting Point：

184-186 °C

Boiling Point：

699.3±55.0°C at 760 mmHg

Flash Point：

218.8±25.0 °C

Refractive Index：

1.568

Water Solubility：

DMSO: soluble 10mg/mL, clear

Storage Conditions：

2-8°C

Toxicity：

Oral-Mouse LD50: 14 mg/kg; Abdominal cavity-mouse LD50: 1 mg/kg

Flammability characteristics：

Flammable, spicy and irritating smoke emitted from the fire

Specific rotation：

D25 +88° (c = 1.55 in ethanol)

Safety Information

Packing level：

Ⅰ

Hazard category：

6.1

Transport codes：

UN 2811 6.1 / PGI

wgk germany：

hazard class code：

safety instructions：

45-24/25

RTECS Number：

RC6190000

Marks：

Storage features：

Treasury is low temperature, ventilated, dry; stored separately from food raw materials

Precautionary statement(s)：

P264; P301 + P310

Hazard Statements：

H300

Toxicity

Toxicity class：

most toxic

Recommended Suppliers of (+)-Cucurbitacin B

Wuhan Pnq Int Trade Co., Ltd Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of Apigenin,PQQ,NMNH

Cucurbitacin B

Unit Price: $10 /G EXW

CAS No.: 6199-67-3

Grade: Chemical Grade

Content: 99%

Inquiry
HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

Cucurbitacin B

CAS No.: 6199-67-3

Content: 99.00%

Inquiry
Henan Lihao Chem Plant Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of PVC resin,pvc paste resin,melamine

CUCURBITACIN B 99% white powder kanbei

CAS No.: 6199-67-3

Grade: Industrial Grade

Content: 99%

Inquiry
Shandong Airuike Chemical Co., Ltd. Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals,CATALYST AND AUXILIARY,FLAVORS AND FRAGRANCES,Chemical Pesticides,ADDITIVE

CUCURBITACIN B CAS 6199-67-3 hot sale

CAS No.: 6199-67-3

Grade: Analytical Reagent

Content: 99%

Inquiry

Learn More Other Chemicals

Fumitremorgin B

12626-17-4
dehydrobruceine B

53730-90-8
(-)-6-Deoxyerythronolide B

15797-36-1
cyanosafracin B Formula

96996-50-8
3''-Deoxyrubradirin B Formula

69279-50-1
Epelmycin B Formula

107807-24-9
Rubrofusarin B Structure

17276-15-2
CARATUBERSIDE B Structure

119767-18-9
What is 7-Hydroxyaloin B

82461-12-9
What is EVERNINOMICIN B SODIUM SALT

53296-30-3

Hot Searches: common peroneal nerve injury; t butyl alcohol; hexanoate; naoh sds; carbonyl sulfide; hongdenafil

Guide of (+)-Cucurbitacin B

Description
Basic Attributes
Characteristics
Safety Information
Toxicity
Recommended Suppliers
Learn More Other Chemicals

(+)-Cucurbitacin B

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.