7-Hydroxyflavone
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7-Hydroxyflavone
structure -
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CAS No:
6665-86-7
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Formula:
C15H10O3
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Chemical Name:
7-Hydroxyflavone
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Synonyms:
4H-1-Benzopyran-4-one,7-hydroxy-2-phenyl-;Flavone,7-hydroxy-;7-Hydroxy-2-phenyl-4H-1-benzopyran-4-one;7-Hydroxyflavone;NSC 94258;7-Hydroxy-2-phenyl-4H-chromen-4-one;7-Hydroxy-2-phenylchromone
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CAS No:
Description
7-Hydroxyflavone is a flavonoid isolated from M. indica, with anti-inflammatory activity. 7-Hydroxyflavone protects renal cells from nicotine (NIC)-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway[1][2].
Safety Information
3
36/37/38
26-37/39
Xi
Irritant
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
H315
7-Hydroxyflavone Use and Manufacturing
Acetylation of m-phenol acetic acid gives 2, 4-dihydroxyacetophenone, which is then benzoylated to obtain (2-hydroxy-4-benzoyloxy)benzoylacetophenone. It was further cyclized at 103°C for 7 hours in a mixture of acetic acid and hydrochloric acid to obtain 7-hydroxyflavone.
antifungal, analgesic
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