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Thiamylal

Thiamylal structure

CAS No:
77-27-0
Formula:
C12H18N2O2S
Chemical Name:
Thiamylal
Synonyms:
4,6(1H,5H)-Pyrimidinedione,dihydro-5-(1-methylbutyl)-5-(2-propen-1-yl)-2-thioxo-;Barbituric acid,5-allyl-5-(1-methylbutyl)-2-thio-;4,6(1H,5H)-Pyrimidinedione,dihydro-5-(1-methylbutyl)-5-(2-propenyl)-2-thioxo-;Dihydro-5-(1-methylbutyl)-5-(2-propen-1-yl)-2-thioxo-4,6(1H,5H)-pyrimidinedione;5-Allyl-5-(1-methylbutyl)-2-thiobarbituric acid;Thiamylal;Thioseconal;Bio-Tal;NSC 120815;1340-07-4;7187-63-5
Categories:
Analytical Chemistry > Standard

Description

ChEBI: A member of the class of barbiturates that is 2-thioxodihydropyrimidine-4,6(1H,5H)-dione substituted by a pentan-2-yl and prop-2-en-1-yl group at position 5.

Thiamylal Basic Attributes

Molecular Weight：

254.35

Exact Mass：

254.35

EC Number：

201-018-3

HScode：

2933530015

Characteristics

PSA：

90.29000

XLogP3：

2.17360

Appearance：

Solid

Density：

1.16g/cm3

Melting Point：

132-133 °C

Refractive Index：

1.551

Water Solubility：

1.298g/L(25 ºC)

Toxicity：

Intravenous-rat LD50: 66 mg/kg; Intravenous-rabbit LD50: 26 mg/kg

Flammability characteristics：

Flammable; burning produces toxic sulfur oxides, nitrogen oxide fumes

PKA：

7.48None

Safety Information

Packing level：

III

Hazard category：

6.1(b)

Transport codes：

3249

wgk germany：

hazard class code：

23/24/25

safety instructions：

36/37/39-45

Marks：

Storage features：

Treasury is ventilated, low temperature and dry; stored separately from food materials

Precautionary statement(s)：

P261-P280-P301 + P310-P311

Hazard Statements：

H301-H311-H331

Toxicity

Toxicity class：

highly toxic

Thiamylal Use and Manufacturing

Thiamylal is a barbiturate derivative with sedative, anticonvulsant and hypnotic effects. Thiamylal is used for induction in surgical anaesthesia as well as an anticonvulsant to counteract side effects from other anaesthetics. Thiamylal is a Controlled Substance.