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Phthalimidoacetyl chloride

Phthalimidoacetyl chloride structure

Phthalimidoacetyl chloride 

structure
  • CAS No:

    6780-38-7

  • Formula:

    C10H6ClNO3

  • Chemical Name:

    Phthalimidoacetyl chloride

  • Synonyms:

    2H-Isoindole-2-acetyl chloride,1,3-dihydro-1,3-dioxo-;2-Isoindolineacetyl chloride,1,3-dioxo-;1,3-Dihydro-1,3-dioxo-2H-isoindole-2-acetyl chloride;Phthalimidoacetyl chloride;Phthalylglycyl chloride;N-Phthaloylglycyl chloride;2-Phthalimidoacetyl chloride;Phthalylglycine acid chloride;N-(Phthaloyl)glycinoyl chloride;(1,3-Dioxo-1,3-dihydroisoindol-2-yl)acetyl chloride;NSC 401729;(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl chloride;2-(1,3-Dioxoisoindolin-2-yl)acetyl chloride;2-Phthalimidoylacetyl chloride;2-(1,3-Dioxoisoindol-2-yl)acetyl chloride;2-(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl)acetyl chloride

  • Categories:

    Chemical Reagents  >  Organic Reagents

Description

slight yellow to white crystalline powder

Phthalimidoacetyl chloride Basic Attributes

223.61

223.61

229-840-8

401729

DTXSID10218053

2925190090

Characteristics

54.4

1.9

1.5±0.1 g/cm3

84-85 °C

190-192 °C @ Press: 15 Torr

161.4±23.2 °C

1.615

Safety Information

IRRITANT

UN 2923 8/PG 3

3

25-34

26-36/37/39-45

T

P280-P305 + P351 + P338-P310

H301-H314

|Danger|H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]|P260, P264, P270, P280, P301+P310, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P330, P363, P405, and P501|Aggregated GHS information provided by 39 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Phthalimidoacetyl chloride Use and Manufacturing

Reactant involved in:• ;Synthesis of selenium-containing amino acid analogs with bactericidal and antifungal activity1• ;Photoinduced single electron transfer cyclization for preparation of cyclic peptides2• ;Arndt-Eistert synthesis3• ;Mitsunobu and arbuzov-type multicomponent pathway4• ;Remote C-H bond functionalization5• ;Amido-alkylation for synthesis of benzofuran derivatives6

Computed Properties

Molecular Weight:223.61
XLogP3:1.9
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:223.0036207
Monoisotopic Mass:223.0036207
Topological Polar Surface Area:54.4
Heavy Atom Count:15
Complexity:305
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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