Aluminum monostearate
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Aluminum monostearate
structure -
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CAS No:
7047-84-9
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Formula:
C18H37AlO4
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Chemical Name:
Aluminum monostearate
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Synonyms:
Aluminum,dihydroxy(octadecanoato-κO)-;Aluminum,dihydroxy(stearato)-;Aluminum,dihydroxy(octadecanoato-O)-;Octadecanoic acid,aluminum complex;Dihydroxy(octadecanoato-κO)aluminum;Aluminum monostearate;Dihydroxyaluminum stearate;Aluminum dihydroxide stearate;Dibasic aluminum stearate;Al-St 103;Aluminum Stearate 300;Aluminum Monostearate 300;3343-54-2
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CAS No:
Description
Fine, white to yellowish-white powder; faint characteristic odor. Insoluble in water, alcohol, and ether. Forms a gel with aliphatic and aromatic hydrocarbons. Aluminum monostearate is an aluminum compound of stearic acid
and palmitic acid. The USP32–NF27 states that aluminum
monostearate contains the equivalent of not less than 14.5% and
not more than 16.5% of Al
2
O
3
, calculated on the dried basis. The
JP XV states that it contains not less than 7.2% and not more than
8.9%
DryPowder
Dihydroxy(stearato)aluminium is an aluminium coordination entity. It derives from an aluminium hydroxide.|Aluminium monostearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2. Also known as dihydroxyaluminium or dihydroxy(stearato)aluminium, it is used to form gels in the packaging of pharmaceuticals and in the preparation of colors for cosmetics. While considered safe for use, extensive usage may result in aluminum accumulation.
Characteristics
28.3
-1.85
powder
1.020
155 °C
359.4ºC at 760 mmHg
162.4ºC
insoluble H2O; forms gel with aliphatic and aromatic hydrocarbons [HAW93]
Aluminum monostearate should be stored in a well-closed container in a cool, dry, place. It is stable under ordinary conditions of use and storage.
Decomposes in the heat to stimulate smoke
Drug Information
Antacids perform a neutralization reaction, ie. they buffer gastric acid, raising the pH to reduce acidity in the stomach. When gastric hydrochloric acid reaches the nerves in the gasitrointestinal mucosa, they signal pain to the central nervous system. This happens when these nerves are exposed, as in peptic ulcers. The gastric acid may also reach ulcers in the esophagus or the duodenum. Other mechanisms may contribute, such as the effect of aluminum ions inhibiting smooth muscle cell contraction and delaying gastric emptying. Aluminum is known to bind troponin C (a muscle protein) and to interfere with voltage-dependent calcium transport. Aluminum also binds to and inhibits the activity of mitochondrial voltage gated channels (VDAC).
aluminum monostearate
Aluminum monostearate Use and Manufacturing
Paints, inks, greases, waxes, thickening lubricating oils; waterproofing, gloss producer, stabilizer for plastics, food additive.
Paint additives and coating additives not described by other categories
Paints and coatings
Paint and coating manufacturing|Aluminum, dihydroxy(octadecanoato-.kappa.O)-: ACTIVE
Cosmetics -> Anticaking; Cosmetic colorant
Computed Properties
Molecular Weight:346.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:18
Exact Mass:346.2663731
Monoisotopic Mass:346.2663731
Topological Polar Surface Area:28.3
Heavy Atom Count:23
Complexity:225
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes
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