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Oleandomycin phosphate

Oleandomycin phosphate structure

Oleandomycin phosphate 

structure
  • CAS No:

    7060-74-4

  • Formula:

    C35H61NO12.H3O4P

  • Chemical Name:

    Oleandomycin phosphate

  • Synonyms:

    Oleandomycin,phosphate (1:1) (salt);Oleandomycin phosphate;1,9-Dioxaspiro[2.13]hexadecane,oleandomycin deriv.;Matromycin;16726-37-7

  • Categories:

    Active Pharmaceutical Ingredients  >  Antibiotics

Description

Oleandomycin Phosphate is the phosphate salt form of oleandomycin, a macrolide antibiotic similar to erythromycin with antimicrobial activity. Oleandomycin targets and reversibly binds to the 50S subunit of bacterial ribosomes. This prevents translocation of peptidyl tRNA leading to an inhibition of protein synthesis.|Antibiotic macrolide produced by Streptomyces antibioticus.

Oleandomycin phosphate Basic Attributes

785.85

785.396301

230-351-7

8681H0C27P

DTXSID9045398

C61865

Characteristics

253.55000

0.97990

145-147 °C

0-6°C

LD50 ivn-rat: 480 mg/kg ANTCAO 7,419,57

Safety Information

UN28116.1/PG2

28

22-24/25-45-36/37-28

RJ9800000

T+

|Danger|H300 (97.62%): Fatal if swallowed [Danger Acute toxicity, oral]|P264, P270, P301+P310, P321, P330, P405, and P501|Aggregated GHS information provided by 42 companies from 2 notifications to the ECHA C&L Inventory.

Drug Information

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

Oleandomycin

Computed Properties

Molecular Weight:785.9
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:17
Rotatable Bond Count:6
Exact Mass:785.39627195
Monoisotopic Mass:785.39627195
Topological Polar Surface Area:244
Heavy Atom Count:53
Complexity:1140
Defined Atom Stereocenter Count:18
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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