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Erythromycin thiocyanate

Erythromycin thiocyanate structure

CAS No:
7704-67-8
Formula:
C37H67NO13.CHNS
Chemical Name:
Erythromycin thiocyanate
Synonyms:
Erythromycin,thiocyanate (salt);Erythromycin thiocyanate;Thiocyanic acid,compd. with erythromycin (1:1);Oxacyclotetradecane,erythromycin deriv.;Gallimycin 10;Gallimycin 50;Erytrovet;Pro-Gallimycin 10;Bactenix V 300;Erythrocin thiocyanate;1286-15-3;1336-59-0;8052-90-2;14485-24-6;1187396-59-3
Categories:
Active Pharmaceutical Ingredients > Antibiotics

Description

Erythromycin thiocyanate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin thiocyanate acts by binding to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1].

Erythromycin thiocyanate Basic Attributes

Molecular Weight：

793.01700

Exact Mass：

792.44400

EC Number：

231-723-1

UNII：

Y7A95YRI88

DSSTox ID：

DTXSID50858755

HScode：

2941500000

Characteristics

PSA：

256.50000

XLogP3：

2.18288

Melting Point：

166-167 °C

Boiling Point：

818.4ºC at 760 mmHg

Flash Point：

448.8ºC

Safety Information

Precautionary statement(s)：

P264, P280, P305+P351+P338, P33, P313

Hazard Statements：

H319

GHS Classification：

|Warning|H319 (98%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]|P264, P280, P305+P351+P338, and P337+P313|Aggregated GHS information provided by 51 companies from 3 notifications to the ECHA C&L Inventory.

Drug Information

MeSH Entry Terms：

erythromycin thiocyanate

Erythromycin thiocyanate Use and Manufacturing

Uses

Antibiotic raw materials and pharmaceutical intermediates are mainly used to treat infections caused by penicillin-resistant staphylococci and streptococci.

Use Classification：

Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients

Computed Properties

Molecular Weight:793.0
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:16
Rotatable Bond Count:7
Exact Mass:792.44421140
Monoisotopic Mass:792.44421140
Topological Polar Surface Area:219
Heavy Atom Count:54
Complexity:1210
Defined Atom Stereocenter Count:18
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Material

Erythromycin

Downstream Products

Erythromycin

Price Analysis

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