Carbenoxolone sodium
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Carbenoxolone sodium
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CAS No:
7421-40-1
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Formula:
C34H50O7.2Na
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Chemical Name:
Carbenoxolone sodium
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Synonyms:
Olean-12-en-29-oic acid,3-(3-carboxy-1-oxopropoxy)-11-oxo-,sodium salt (1:2),(3β,20β)-;Olean-12-en-30-oic acid,3β-hydroxy-11-oxo-,hydrogen succinate,disodium salt;Olean-12-en-29-oic acid,3-(3-carboxy-1-oxopropoxy)-11-oxo-,disodium salt,(3β,20β)-;Carbenoxolone sodium;Sodium carbenoxolone;Glycyrrhetinic acid hydrogen succinate disodium salt;Carbenoxolone sodium salt;Glycyrrhetinic acid succinate disodium salt;Carbenoxolone disodium;Glycyrrhetic acid hydrosuccinate disodium salt;Disodium glycyrrhetic acid hemisuccinate;Disodium glycyrrhetinyl succinate;Carbenoxolone disodium salt;3-(Succinyloxy)glycyrrhetic acid disodium salt;Carbenoxalone disodium salt;Ulcus-Tablinen;Neogel;Pyrogastrone;Duogastrone;Sanodin;Carbenoxalone sodium;Bioral;37750-77-9;82934-50-7;885460-43-5;152014-12-5;906323-02-2
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CAS No:
Characteristics
123.63000
4.15890
687.4ºC at 760 mmHg
211.6ºC
Soluble in water to 100 mM.
2-8°C
Oral-rat LD50: 2450 mg/kg; Abdominal cavity-mouse LD50: 120 mg/kg
Thermal decomposition to emit toxic sodium oxide fumes
Safety Information
3
22-36
26-36
RK0250000
Xn,Xi
The warehouse is low-temperature, ventilated and dry
Drug Function and Efficacy
Increase the mucus secretion of gastric mucosa, promote the repair of gastric mucosal epithelial cells, prevent the reverse diffusion of hydrogen ions, and strengthen the gastric mucosal barrier; combine with pepsin, inhibit the enzyme activity by about 50%, and have a protective effect on the ulcer surface; stimulate the adrenal glands or enhance the effect of endogenous corticosteroids.
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