Terazosin monohydrochloride dihydrate
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Terazosin monohydrochloride dihydrate
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CAS No:
70024-40-7
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Formula:
C19H25N5O4.ClH.2H2O
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Chemical Name:
Terazosin monohydrochloride dihydrate
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Synonyms:
Methanone,[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-,hydrochloride,hydrate (1:1:2);Piperazine,1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-,monohydrochloride,dihydrate;Terazosin monohydrochloride dihydrate;Terazosin hydrochloride dihydrate
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CAS No:
Description
Terazosin Hydrochloride dihydrate is a selective alpha1-antagonist used for treatment of symptoms of benign prostatic hyperplasia (BPH).Target: Alpha-1 Adrenergic ReceptorTerazosin Hydrochloride dihydrate is an a1-selective blocker. Its inhibitory effect on prostate tumor growth may be the result of antiangiogenic activity. Terazosin Hydrochloride dihydrate is an inhibitor of α1A-AR, α1B-AR, α1D-AR and α2B-AR [1].
Safety Information
NONH for all modes of transport
22
TK8046000
Xn
P301 + P312 + P330
H302
|Warning|H302 (64.79%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P280, P301+P312, P305+P351+P338, P330, P337+P313, and P501|Aggregated GHS information provided by 142 companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
Drugs used in the treatment of urogenital conditions and diseases such as URINARY INCONTINENCE; PROSTATIC HYPERPLASIA; and ERECTILE DYSFUNCTION. (See all compounds classified as Urological Agents.)|Drugs that bind to and block the activation of ADRENERGIC ALPHA-1 RECEPTORS. (See all compounds classified as Adrenergic alpha-1 Receptor Antagonists.)
A 45975
Terazosin monohydrochloride dihydrate Use and Manufacturing
analgesic, antiinflammatory
Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
Computed Properties
Molecular Weight:459.9
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:4
Exact Mass:459.1884614
Monoisotopic Mass:459.1884614
Topological Polar Surface Area:105
Heavy Atom Count:31
Complexity:544
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:4
Compound Is Canonicalized:Yes
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Terazosin monohydrochloride dihydrate
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