 Home > Encyclopedia > Salicylanilide

Salicylanilide

Salicylanilide structure

CAS No:
87-17-2
Formula:
C13H11NO2
Chemical Name:
Salicylanilide
Synonyms:
Benzamide,2-hydroxy-N-phenyl-;Salicylanilide;2-Hydroxy-N-phenylbenzamide;Ansadol;Aseptolan;o-Hydroxybenzanilide;2-Hydroxybenzanilide;Salicylanilid;Salinide;Salinidol;Salnide;Shirlan AG;Shirlan;Shirlan Extra;Salicylic acid anilide;N-Phenylsalicylamide;Sherstat SLN;Hyanilid;Salifebrin;WR 10019;2-(N-Phenylcarboxamido)phenol;SA 88;2-(Phenylaminocarbonyl)phenol;N-Phenyl-2-hydroxybenzamide;NSC 14881;SA 88 (biocide)
Categories:
Organic Chemistry > Amides

Description

Salicylanilide demonstrates a wide range of biological activities including antiviral potency which can inhibit HIV virus by targeting HIV-1 integrase or reverse transcriptase.

Salicylanilide is an amide of salicylic acid and of aniline; it is therefore both a salicylamide and an anilide. It is a member of salicylamides, a member of salicylanilides and a benzanilide fungicide.

Salicylanilide Basic Attributes

Molecular Weight：

213.23

Exact Mass：

213.23

EC Number：

201-727-8

UNII：

LHP8NEY345

NSC Number：

755836|14881

DSSTox ID：

DTXSID7021784

HScode：

2924299090

Characteristics

PSA：

49.3

XLogP3：

3.3

Appearance：

white to off-white crystalline powder

Density：

1.33 g/cm³

Melting Point：

136.5 °C

Boiling Point：

294.3ºC at 760 mmHg

Flash Point：

131.8±22.6 °C

Refractive Index：

1.676

Water Solubility：

H2O: SLIGHTLY soluble

Storage Conditions：

-20°C

Toxicity：

Oral-Mouse LD50: 2400 mg/kg

Flammability characteristics：

Combustion produces toxic nitrogen oxide gas

Collision Cross Section：

143.9 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Safety Information

Transport codes：

UN 3077 9 / PGIII

wgk germany：

hazard class code：

36/37/38

safety instructions：

26-37/39-36

RTECS Number：

VN7850000

Marks：

Storage features：

The warehouse is ventilated, low temperature and dry; stored and transported separately from food materials

Stability/Shelf Life：

Stable under normal temperatures and pressures.

Precautionary statement(s)：

P261-P273-P305 + P351 + P338

Hazard Statements：

H315-H319-H335-H400

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P391, P403+P233, P405, and P501|Aggregated GHS information provided by 585 companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Toxicity

Toxicity class：

moderately toxic

Drug Information

MeSH Entry Terms：

salicylanilide

Salicylanilide Use and Manufacturing

Uses

Anti-mildew, fungicide.

Manufacturing Info：

Benzamide, 2-hydroxy-N-phenyl-: ACTIVE

Computed Properties

Molecular Weight:213.23
XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:213.078978594
Monoisotopic Mass:213.078978594
Topological Polar Surface Area:49.3
Heavy Atom Count:16
Complexity:236
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Carbon tetrachloride

Drug Function and Efficacy

Antifungal drugs

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Compound aniline methyl salicylate cream
Ingredients	This product is a compound preparation, each gram containing 0.05 grams of salicylanilide, 0.01 grams of methyl salicylate, and 0.01 grams of borneol.
Indication	1. Do not use with drugs containing iron or other metals. 2. If used with other drugs at the same time, drug interactions may occur. Please consult your doctor or pharmacist for details.
Specifications	Compound
Manufacturer	Mayinglong Pharmaceutical Group Co., Ltd.

Compound aniline methyl salicylate cream
Ingredients	This product is a compound preparation, each gram containing 0.05 grams of salicylanilide, 0.01 grams of methyl salicylate, and 0.01 grams of borneol.
Indication	1. Do not use with drugs containing iron or other metals. 2. If used with other drugs at the same time, drug interactions may occur. Please consult your doctor or pharmacist for details.
Specifications	Compound

Recommended Suppliers of Salicylanilide

LEADER BIOCHEMICAL GROUP Contact Supplier

CN
8 YRS

Business licensed Certified factory

Manufactory Supplier of Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients,Natural Plant Ingredients,APIS Intermidiates,Daily Chemicals,Agricultural Chemicals,Surfactant Chemicals,Ultraviolet Absorbents,Antioxidant Ingredients,Scientific Research Chemical,Flavors and Fragrances Chemicals

China Most Professional Factory Supply High Qulity Salicylanilide CAS 87-17-2

CAS No.: 87-17-2

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Henan Lihao Chem Plant Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of PVC resin,pvc paste resin,melamine

Salicylanilide CAS 87-17-2 99% a white or almost white crystalline powder kanbei

CAS No.: 87-17-2

Content: 99%

Inquiry
Hangzhou Chungyo Chemicals Co., Ltd. Contact Supplier

CN
3 YRS

Business licensed Certified factory

Manufactory Supplier of Dyes,Textile agent,Medical intermediate,API,Pigments,Basic Chemicals

Salicylanilid

CAS No.: 87-17-2

Grade: pharmaceutical grade

Content: 98%

Inquiry