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Iron sucrose

Iron sucrose structure

CAS No:
8047-67-4
Chemical Name:
Iron sucrose
Synonyms:
Iron saccharate;Glucaric acid,iron derivs.,D-;Colliron IV;Feojectin;Ferrivenin;Neoferrum;Iron oxide saccharated;Iron sugar;Proferrin;Saccharated iron;Sucrofer;Hippiron;Fesin;Venofer;Ferric hydroxide sucrose complex;Saccharated iron oxide;Ferrum Hausmann i.v.;Iron(III) hydroxide sucrose complex;Venoferrum;Iron sucrose complex;Saccharated ferric oxide;Iron sucrose;XI 921;Ferum Hausmann;Ferrum vitis;Ferplex SS;Ferijet;Ferosoft S;Encifer;Fe-back;Fe-lib;Sucroferric oxyhydroxide;PA 21;PA 21 (phosphate binder);Velphoro;12001-35-3;12678-06-7;63530-05-2;1418308-48-1
Categories:
Biochemical Engineering > Saccharides

Description

Brown solid

A glucaric acid-iron conjugate that is used in the treatment of IRON-DEFICIENCY ANEMIA, including in patients with chronic kidney disease, when oral iron therapy is ineffective or impractical.

Iron sucrose Basic Attributes

Molecular Weight：

736.06

Exact Mass：

735.935608

EC Number：

232-464-7

HScode：

3004909090

Characteristics

PSA：

483.54000

XLogP3：

-18.21560

Melting Point：

MORE THAN 51ºC

Boiling Point：

766.4ºC at 760 mmHg

Flash Point：

431.2ºC

Toxicity：

LD50 in mice (mg Fe/kg): >2500 orally; >200 i.v. (Geisser)

Safety Information

GHS Classification：

|Danger|H301 (33.33%): Toxic if swallowed [Danger Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P310, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 4 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH：

Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. They are used in the treatment of anemias. (See all compounds classified as Hematinics.)

MeSH Entry Terms：

D-Glucaric acid, iron(2+) salt (1:1)

Iron sucrose Use and Manufacturing

Iron Saccharate has been used to treat iron deficiency and iron deficiency anemia associated with different chronic diseases.

Computed Properties

Molecular Weight:263.97
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:263.956853
Monoisotopic Mass:263.956853
Topological Polar Surface Area:161
Heavy Atom Count:15
Complexity:191
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Drug Function and Efficacy

No specific pharmacological effects mentioned

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Sucrose Iron
Manufacturer	Techpool BIO-PHARMA Co., Ltd.

Iron Sucrose Injection
Ingredients	The main ingredients and chemical names of this product are: Sucrose iron Molecular formula: [Na2Fe5O8(OH)·3(H2O)]n·m(C12H22O11) Weight average molecular weight: 34000-60000Da
Indication	Like all parenteral iron preparations, this product will reduce the absorption of oral iron, so this product should not be used at the same time as oral iron. Therefore, oral iron treatment should be started 5 days after the injection of this product.
Specifications	10ml:200mg(iron)
Manufacturer	Nanjing Hencer Pharmaceutical Co., Ltd.

Iron Sucrose Injection
Ingredients	Sucrose Iron
Indication	Like all parenteral iron preparations, this product will reduce the absorption of oral iron, so this product should not be used at the same time as oral iron. Therefore, oral iron treatment should be started 5 days after the injection of this product.
Specifications	5 ml: 100 mg iron and 1.6 g sucrose

See More Related Drugs

Registered Holders

SNJ LABS PVT LTD

United States
Active
YABAO PHARMACEUTICAL GROUP CO LTD

United States
Active
BIOPHORE INDIA PHARMACEUTICALS PVT LTD

United States
Active

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Learn More Other Chemicals

Calcium iron oxide (Ca2Fe2O5)

12013-62-6
Iron cyanide (Fe(CN)3)

5683-74-9
Iron alloy, base, Fe 72,Cr 28

11109-79-8
Hexanoic acid, 3,5,5-trimethyl-, iron salt (1:?) Formula

68213-78-5
Aluminum, compd. with iron (1:3) Formula

12003-42-8
Aluminum iron oxide (AlFe2O4) Formula

58942-78-2
Aluminum, compd. with iron (3:1) Structure

12004-62-5
IRON (III) ISOPROPOXIDE Structure

14995-22-3
What is Iron selenide (FeSe)

1310-32-3
What is Iron hydroxide sulfate (Fe4(OH)2(SO4)5)

1310-45-8

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Guide of Iron sucrose

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
Learn More Other Chemicals

Iron sucrose

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