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Sanggenon C

Sanggenon C structure

Sanggenon C 

structure
  • CAS No:

    80651-76-9

  • Formula:

    C40H36O12

  • Chemical Name:

    Sanggenon C

  • Synonyms:

    11H-Benzofuro[3,2-b][1]benzopyran-11-one,2-[(1S,5S,6R)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-5a,10a-dihydro-1,3,8,10a-tetrahydroxy-5a-(3-methyl-2-buten-1-yl)-,(5aR,10aS)-;11H-Benzofuro[3,2-b][1]benzopyran-11-one,2-[6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-5a,10a-dihydro-1,3,8,10a-tetrahydroxy-5a-(3-methyl-2-butenyl)-;11H-Benzofuro[3,2-b][1]benzopyran-11-one,2-[(1S,5S,6R)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-5a,10a-dihydro-1,3,8,10a-tetrahydroxy-5a-(3-methyl-2-butenyl)-,(5aR,10aS)-;(5aR,10aS)-2-[(1S,5S,6R)-6-(2,4-Dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-5a,10a-dihydro-1,3,8,10a-tetrahydroxy-5a-(3-methyl-2-buten-1-yl)-11H-benzofuro[3,2-b][1]benzopyran-11-one;Sanggenone C;Sanggenon C

  • Categories:

    Biochemical Engineering  >  Plant Extracts

Description

Sanggenon C is a flavanone Diels-Alder adduct compound, which is isolated from the root bark of Morus cathayana. Sanggenon C exerts protective effects against cardiac hypertrophy and fibrosis via suppression of the calcineurin/NFAT2 pathway. Sanggenon C inhibits inducible nitric oxide synthase expression in RAW264.7 cells, and tumor necrosis factor-α-stimulated cell adhesion and vascular cell adhesion molecule-1 expression, by suppressing NF-κB activity[1]. Sanggenon C possesses antioxid


Sanggenon C is a diarylheptanoid.

Sanggenon C Basic Attributes

708.712

708.71

DTXSID20230468

Characteristics

214.44000

7.94

1.5±0.1 g/cm3

999.3±65.0 °C at 760 mmHg

312.7±27.8 °C

1.727

Drug Information

cathayanon E

Computed Properties

Molecular Weight:708.7
XLogP3:6.3
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:6
Exact Mass:708.22067658
Monoisotopic Mass:708.22067658
Topological Polar Surface Area:214
Heavy Atom Count:52
Complexity:1430
Defined Atom Stereocenter Count:3
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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