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Ganoderic acid A

Ganoderic acid A structure

Ganoderic acid A 

structure
  • CAS No:

    81907-62-2

  • Formula:

    C30H44O7

  • Chemical Name:

    Ganoderic acid A

  • Synonyms:

    Lanost-8-en-26-oic acid,7,15-dihydroxy-3,11,23-trioxo-,(7β,15α,25R)-;(7β,15α,25R)-7,15-Dihydroxy-3,11,23-trioxolanost-8-en-26-oic acid;Ganoderic acid A

  • Categories:

    Biochemical Engineering  >  Plant Extracts

Description

Ganoderic acid can Inhibitt of the JAK-STAT3 signaling pathway, also inhibit proliferation, viability, ROS.In vitro: A lower doses of Ganoderic acid enhance HLA class II-mediated antigen presentation and CD4+ T cell recognition of lymphoma. [1] ganoderic acid A promots cisplatin-induced cell death by enhancing the sensitivity of HepG2 cells to cisplatin mainly via the signal transducer and activator of transcription 3 suppression. [2] Ganoderic acid A inhibits proliferation, viability, R


Ganoderic acid A is a triterpenoid.

Ganoderic acid A Basic Attributes

514.65

516.67

548G37DF65

29189900

Characteristics

129

4.05160

1.2±0.1 g/cm3

118-123 °C

690.1±55.0°C at 760 mmHg

391.3±29.4 °C

1.575

Safety Information

NONH for all modes of transport

24/25

Drug Information

ganoderic acid A

Computed Properties

Molecular Weight:516.7
XLogP3:2.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:516.30870374
Monoisotopic Mass:516.30870374
Topological Polar Surface Area:129
Heavy Atom Count:37
Complexity:1070
Defined Atom Stereocenter Count:9
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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