Cefteram pivoxil
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Cefteram pivoxil
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CAS No:
82547-81-7
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Formula:
C22H27N9O7S2
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Chemical Name:
Cefteram pivoxil
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Synonyms:
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-,(2,2-dimethyl-1-oxopropoxy)methyl ester,(6R,7R)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-,(2,2-dimethyl-1-oxopropoxy)methyl ester,[6R-[6α,7β(Z)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-,(2,2-dimethyl-1-oxopropoxy)methyl ester,(6R,7R)-;T 2588;Antibiotic T 2588;Ro 19-5248;Cefteram pivoxil;Tomiron 100;Tomiron
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CAS No:
Characteristics
259.65000
0.72490
1.66 g/cm3
125-128°C
1.744
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
LD50 in male, female mice, rats (g/kg): >6.00, 5.86, 5.63, 5.09 i.p.; in both species >6.00 s.c.; in male mice, rats, dogs (g/kg): >6.00, >6.00, >2.00 orally (Sato)
Drug Information
Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)
cefteram pivoxil
Cefteram pivoxil Use and Manufacturing
Third generation, orally active cephalosporin antibiotic. Antibacterial.
Computed Properties
Molecular Weight:593.6
XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:12
Exact Mass:593.14748658
Monoisotopic Mass:593.14748658
Topological Polar Surface Area:260
Heavy Atom Count:40
Complexity:1100
Undefined Atom Stereocenter Count:2
Undefined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Not yet clear
Registered Holders
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Shandong Ruiying Pioneer Pharmaceutical Co., Ltd.
Active
China
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Hainan Simcere Pharmaceutical Co., Ltd.
Active
China
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Qilu Antibiotics Pharmaceutical Co., Ltd.
Active
China
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