Astragaloside A
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Astragaloside A
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CAS No:
83207-58-3
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Formula:
C41H68O14
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Chemical Name:
Astragaloside A
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Synonyms:
β-D-Glucopyranoside,(3β,6α,16β,24R)-20,24-epoxy-16,25-dihydroxy-3-(β-D-xylopyranosyloxy)-9,19-cyclolanostan-6-yl;1H,19H-Cyclopropa[9,10]cyclopenta[a]phenanthrene,β-D-glucopyranoside deriv.;9,19-Cyclolanostane,β-D-glucopyranoside deriv.;(3β,6α,16β,24R)-20,24-Epoxy-16,25-dihydroxy-3-(β-D-xylopyranosyloxy)-9,19-cyclolanostan-6-yl β-D-glucopyranoside;Astramembrannin I;Astragaloside A;Astragalin A
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CAS No:
Description
Astragaloside A is one of the major active constituents of Astragalus membranaceus in Traditional Chinese Medicine; has been widely used to treat ischemic diseases.IC50 value: Target: in vitro: AS-IV treatment promotes umbilical vein endothelial cells (HUVEC) proliferation, migration, and tube formation. AS-IV treatment also activates JAK2/STAT3 and ERK1/2 signaling pathways, and up-regulates endothelial nitric oxide synthase (eNOS) expression and nitric oxide (NO) production [1]. Admini
Astragaloside A Use and Manufacturing
Astragaloside A is the isomer of Astragaloside IV. Astragaloside A has protective effects on cardiovascular, immune , digestive and nervous system.
Computed Properties
Molecular Weight:785.0
XLogP3:1.3
Hydrogen Bond Donor Count:9
Hydrogen Bond Acceptor Count:14
Rotatable Bond Count:7
Exact Mass:784.46090684
Monoisotopic Mass:784.46090684
Topological Polar Surface Area:228
Heavy Atom Count:55
Complexity:1460
Defined Atom Stereocenter Count:19
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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