2,4-Dichlorobenzenemethanamine

clear colourless liquid

General procedure: A mixture of benzaldehyde oxime (0.121 g, 1 mmol) and nano Fe3O4 (0.046 g, 0.2 mmol) (nano particle size≈70 nm) was ground in a porcelain mortar. ZrCl4 (0.233 g, 1 mmol) was then added and grinding the mixture was continued for a moment at room temperature. The mortar was heated in an oil bath until the temperature of reaction mixture reaches 75–80 °C. NaBH3CN (0.314 g, 5 mmol) wasthen added portion wisely and the mixture was ground for15 min at 75–80 °C. After completion of the reaction, H2O(5 mL) was added and the mixture was stirred for 5 min. The mixture was extracted with EtOAc (2 × 5 mL) and then dried over anhydrous Na2SO4. Evaporation of the solvent affords the pure liquid benzylamine in 93 percent yield (0.1 g, Table 2, entry 1).General procedure: In a 25mL round bottom flask, CuNP/WS was added into amixed solution containing 5mL doubly distilled water and 1 mmol nitroarene or benzonitrile. Next, 4 mmol NaBH4 was added in 4 portions to the reaction mixture and stirredat room temperature for the appropriate amount of time. The progress of the reaction was monitored by TLC [usingethyl acetate/n-hexane as eluent: 1/5]. After completion of the reaction, the reaction mixture was filtered off and thecatalyst rinsed twice with dichloromethane. The organic extracts were washed with H2O, dried over MgSO4 and evaporated in vacuo to give corresponding amines.

Molecular Weight:176.04
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:174.9955546
Monoisotopic Mass:174.9955546
Topological Polar Surface Area:26
Heavy Atom Count:10
Complexity:108
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes