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Lactide

Lactide structure

CAS No:
95-96-5
Formula:
C6H8O4
Chemical Name:
Lactide
Synonyms:
1,4-Dioxane-2,5-dione,3,6-dimethyl-;p-Dioxane-2,5-dione,3,6-dimethyl-;Lactide;Lactic acid,bimol. cyclic ester;3,6-Dimethyl-1,4-dioxane-2,5-dione;3,6-Diketo-2,5-dimethyl-1,4-dioxane;3,6-Dimethyl-p-dioxane-2,5-dione;2,5-Dioxo-3,6-dimethyl-1,4-dioxane;Propanoic acid,2-hydroxy-,bimol. cyclic ester;3,6-Dimethyl-2,5-dioxo-1,4-dioxane;2,5-Dimethyl-3,6-dioxo-1,4-dioxane;Dilactide;DL-Lactide;Lactoyl lactic acid;Purasorb DL;NSC 403080;rac-Lactide;Novalact;dl-Dilactide;DL-Dilactide;Dimethylglycolide;D,L-Lactide;Olygos DMR;Ingeo M 700;615-95-2;51019-72-8;87760-46-1;116559-43-4;137566-94-0;153381-12-5;219616-64-5;340821-71-8;612845-77-9;1310566-98-3;1351306-95-0;1415890-67-3;2129300-88-3;2324093-62-9
Categories:
Cosmetic Ingredient > Abrasive

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Description

White crystalline powder

Lactide is a member of dioxanes.

Lactide Basic Attributes

Molecular Weight：

144.13

Exact Mass：

144.13

EC Number：

202-468-3

UNII：

7EH08MWO6M

NSC Number：

403080

DSSTox ID：

DTXSID7041253

HScode：

2934999090

Characteristics

PSA：

52.6

XLogP3：

0.6

Appearance：

White crystalline powder

Density：

1.2±0.1 g/cm3

Melting Point：

129 °C

Boiling Point：

138ºC(8 torr)

Flash Point：

150.6±18.8 °C

Refractive Index：

1.429

Storage Conditions：

Refrigerator (+4ºC)

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

R36/37/38

safety instructions：

S26-S37/39

RTECS Number：

JH1100000

Marks：

Xi:Irritant;

Precautionary statement(s)：

P305 + P351 + P338

Hazard Statements：

H319

GHS Classification：

|Warning|H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]|P264, P280, P305+P351+P338, and P337+P313|Aggregated GHS information provided by 52 companies from 4 notifications to the ECHA C&L Inventory.

Drug Information

MeSH Entry Terms：

3,6-dimethyl-1,4-dioxane-2,5-dione

Lactide Use and Manufacturing

Uses

DL-Lactide is used to produce 2-hydroxy-propionic acid 1-(1-phenyl-ethoxycarbonyl)-ethyl ester. It acts as an important raw material and an intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyes. It is involved in enzymatic alcoholysis to produce both alkyl (R)-lactates and alkyl (S,S)-lactyllactates.DL-Lactide is often used as a protective layer in wound coatings, or as anchors, screws or mesh in surgery, since it degrades in about six months to the innocuous lactic acid. Enzymatic alcoholysis of this racemic lactide catalyzed by commercial Novozym® 435 produces both alkyl (R)-lactates and alkyl (S,S)-lactyllactates in good yield and high enantiopurity.

Manufacturing Info：

1,4-Dioxane-2,5-dione, 3,6-dimethyl-: ACTIVE

Computed Properties

Molecular Weight:144.12
XLogP3:0.6
Hydrogen Bond Acceptor Count:4
Exact Mass:144.04225873
Monoisotopic Mass:144.04225873
Topological Polar Surface Area:52.6
Heavy Atom Count:10
Complexity:155
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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CAS No.: 95-96-5

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Guide of Lactide

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
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Lactide

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