Fenticlor
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Fenticlor
structure -
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CAS No:
97-24-5
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Formula:
C12H8Cl2O2S
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Chemical Name:
Fenticlor
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Synonyms:
Phenol,2,2′-thiobis[4-chloro-;2,2′-Thiobis[4-chlorophenol];D 25;CR 305;Bis(2-hydroxy-5-chlorophenyl) sulfide;Novex;Fenticlor;S 7 (antimycotic);5,5′-Dichloro-2,2′-dihydroxydiphenyl sulfide;Fentichlor;Oksid;2,2′-Dihydroxy-5,5′-dichlorophenyl sulfide;D 25-Antimykotikum;S 7;Ovitrol;HL 1050;Meflorin;Ph 549;2,2′-Dihydroxy-5,5′-dichlorodiphenyl sulfide;NSC 4112;NSC 55636;74082-96-5
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CAS No:
Description
white to pale yellow powder
2,2'-thiobis(4-chlorophenol) appears as white to cream-colored solid or pale yellow powder. White crystalline solid melting from 175.8-186.8°C. Odorless and insoluble in water.
2,2'-thiobis(4-chlorophenol) appears as white to cream-colored solid or pale yellow powder. White crystalline solid melting from 175.8-186.8°C. Odorless and insoluble in water.|Fenticlor is an aryl sulfide having two 5-chloro-2-hydroxyphenyl groups attached to sulfur; an antiinfective drug mostly used in veterinary medicine. It has a role as an antiinfective agent and a drug allergen. It is an aryl sulfide, a member of monochlorobenzenes, a polyphenol and a bridged diphenyl antifungal drug.|Fenticlor is an antibacterial and antifungal agent for topical use, mostly used now in veterinary medicine.
Fenticlor Basic Attributes
287.16
287.16
202-568-7
D61659OVD0
55636|4112
DTXSID4026137
C65671
2930909090
Characteristics
65.8
4.40
2,2'-thiobis(4-chlorophenol) appears as white to cream-colored solid or pale yellow powder. White crystalline solid melting from 175.8-186.8°C. Odorless and insoluble in water.
1.6±0.1 g/cm3
174 °C
416.7±45.0 °C at 760 mmHg
205.8±28.7 °C
1.730
less than 1 mg/mL at 72° F (NTP, 1992)
LDLo intraperitoneal in mouse: 250mg/kg
Insoluble in water.
Sulfides, Organic
2,2'-THIOBIS(4-CHLOROPHENOL) is incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials may generate heat and toxic or flammable gases.
Safety Information
IRRITANT
36/37/38
26-36/37/39
SN0350000
Stable. Incompatible with strong oxidizing agents.
P261, P264, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P333+P313, P362, P363, P403+P233, P405, P501
H315
Flash point data are not available for this chemical, but it is probably combustible. (NTP, 1992)
|Danger|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P333+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Fires involving this compound should be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this material in a refrigerator. (NTP, 1992)
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)
Drug Information
SYMPTOMS: This material may cause skin irritation. ACUTE/CHRONIC HAZARDS: This material may cause irritation of the skin on contact. Hazardous products are emitted when this chemical is heated to decomposition. (NTP, 1992)
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
fentichlor
Fenticlor Use and Manufacturing
Fungicide; especially used against Monosporium apiospermum:Reifferscheid, Seeliger, Dtsch. Med. Wochenschr. 80, 1841, 1850 (1955).
Cosmetics -> Antimicrobial
Computed Properties
Molecular Weight:287.2
XLogP3:4.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:285.9622061
Monoisotopic Mass:285.9622061
Topological Polar Surface Area:65.8
Heavy Atom Count:17
Complexity:231
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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