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Oxolamine

Oxolamine structure

Oxolamine 

structure
  • CAS No:

    959-14-8

  • Formula:

    C14H19N3O

  • Chemical Name:

    Oxolamine

  • Synonyms:

    1,2,4-Oxadiazole-5-ethanamine,N,N-diethyl-3-phenyl-;1,2,4-Oxadiazole,5-[2-(diethylamino)ethyl]-3-phenyl-;N,N-Diethyl-3-phenyl-1,2,4-oxadiazole-5-ethanamine;Oxolamine;5-(2-Diethylaminoethyl)-3-phenyl-1,2,4-oxadiazole;3-Phenyl-5-(β-diethylaminoethyl)-1,2,4-oxadiazole;683M

Description

N,N-diethyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine is an oxadiazole and a ring assembly.|Oxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant. It is listed as a prescription drug in New Zealand legislation. Oxolamine is also approved in Taiwan for the treatment of respiratory tract inflamation.

Oxolamine Basic Attributes

245.32

245.32

213-493-4

90BEA145GY

DTXSID5023403

R - Respiratory system

2934999090

Characteristics

42.2

3.50

1.1±0.1 g/cm3

<25 °C

127 °C

174.4±28.4 °C

1.531

LD50 oral in rat: > 2gm/kg

Drug Information

Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally. (See all compounds classified as Antitussive Agents.)

5-diethylaminoethyl-3-phenyl-1,2,4-oxadiazole

Oxolamine Use and Manufacturing

Oxolamine is a antiinflammatory drug used as a cough suppressant.

Computed Properties

Molecular Weight:245.32
XLogP3:2.9
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:245.152812238
Monoisotopic Mass:245.152812238
Topological Polar Surface Area:42.2
Heavy Atom Count:18
Complexity:227
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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