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Methacycline

Methacycline structure

CAS No:
914-00-1
Formula:
C22H22N2O8
Chemical Name:
Methacycline
Synonyms:
2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-,(4S,4aR,5S,5aR,12aS)-;2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-;2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-,[4S-(4α,4aα,5α,5aα,12aα)]-;(4S,4aR,5S,5aR,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide;4-Dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide;Metacycline;Methacycline;6-Methyleneoxytetracycline;Rondomycin;6-Methylene-5-hydroxytetracycline;Oxytetracycline,6-methylene-;6-Deoxy-6-methylene-6-demethyl-5-hydroxytetracycline;Bialatan;6-Demethyl-6-deoxy-5-hydroxy-6-methylenetetracycline;Tri-methacycline;GS 2876;130604-14-7;2326-40-1;5585-78-4;7285-00-9;10597-93-0;60683-14-9;77506-08-2;82290-85-5;857345-45-0
Categories:
Active Pharmaceutical Ingredients > Antibiotics

Description

ChEBI: A tetracycline that is the 6-methylene analogue of oxytetracycline, obtained by formal dehydration at position 6.

Methacycline Basic Attributes

Molecular Weight：

442.42

Exact Mass：

442.42

EC Number：

213-017-5

Characteristics

PSA：

181.62000

XLogP3：

0.26240

Density：

1.66g/cm3

Melting Point：

205 °C (decomp)

Boiling Point：

695.1ºC at 760mmHg

Flash Point：

374.2ºC

Refractive Index：

1.753

Water Solubility：

7.548g/L(21 ºC)

Safety Information

Stability/Shelf Life：

UNSTABLE IN LIGHT, STABLE @ ROOM TEMP.

Methacycline Use and Manufacturing

Methacycline is a semi-synthetic tetracycline prepared by dehydration of the 6-hydroxy group of oxytetracycline to yield an exocyclic 6-methylene. Like all tetracyclines, methacycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. Methacycline has been extensively cited in the literature with over 400 references.

Recommended Suppliers of Methacycline

Shaanxi Dideu Medichem Co. Ltd Contact Supplier

CN
5 YRS

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METHACYCLINE

CAS No.: 914-00-1

Grade: Pharmaceutical Grade

Content: 99%

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Jinshu Peptide Co.,Ltd Contact Supplier

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3 YRS

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Distributor Supplier of peptone

Factory direct sale metacycline human with Safe Delivery

CAS No.: 914-00-1

Grade: Industrial Grade

Content: 99%

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Baoji Guokang Bio-Technology Co.,Ltd Contact Supplier

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METHACYCLINE Medical Grade

CAS No.: 914-00-1

Grade: Medical Grade

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