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Nifuroxazide

pharmaceutical raw materials
Nifuroxazide structure

Nifuroxazide 

structure
  • CAS No:

    965-52-6

  • Formula:

    C12H9N3O5

  • Chemical Name:

    Nifuroxazide

  • Synonyms:

    Benzoic acid,4-hydroxy-,2-[(5-nitro-2-furanyl)methylene]hydrazide;Benzoic acid,p-hydroxy-,(5-nitrofurfurylidene)hydrazide;Benzoic acid,4-hydroxy-,[(5-nitro-2-furanyl)methylene]hydrazide;RC 30-109;Nifuroxazide;5-Nitro-2-furfurylidene-4-hydroxybenzhydrazide;(5-Nitro-2-furfurylidene)(4-hydroxybenzoyl)hydrazine;p-Hydroxybenzoic acid (5-nitrofurfurylidene)hydrazide;1-(p-Hydroxybenzoyl)-2-(5-nitrofurfurylidene)hydrazine;5-Nitro-2-furaldehyde p-hydroxybenzoylhydrazone;Diarlidan;Dicoferin;Nifuroxazid;Ercefurol;Ercefuryl;27-109RC;Pentofuryl;Bacifurane;RC 27109;Adral;Enterofuril;Antinal

  • Categories:

    Active Pharmaceutical Ingredients  >  Antibiotics

Description

Nifuroxazide is an effective inhibitor of STAT3, also exerts potent anti-tumor and anti-metastasis activity.

Nifuroxazide Basic Attributes

275.22

275.22

213-522-0

DTXSID4045343

A07AX03

2932190090

Characteristics

121

2.1

Yellow solid

1.5±0.1 g/cm3

298 °C

1.653

Refrigerator, Under Inert Atmosphere

LD50 intraperitoneal in mouse: 1gm/kg

Safety Information

NONH for all modes of transport

3

DH2528300

Stable at normal temperatures and pressures.

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, P501

H302

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, and P501|Aggregated GHS information provided by 6 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Nifuroxazide Use and Manufacturing

Uses

Intestinal antiseptic

Pharmaceuticals

Computed Properties

Molecular Weight:275.22
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:275.05422040
Monoisotopic Mass:275.05422040
Topological Polar Surface Area:121
Heavy Atom Count:20
Complexity:387
Undefined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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