Disodium creatine phosphate
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Disodium creatine phosphate
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CAS No:
922-32-7
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Formula:
C4H10N3O5P.2Na
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Chemical Name:
Disodium creatine phosphate
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Synonyms:
Glycine,N-[imino(phosphonoamino)methyl]-N-methyl-,sodium salt (1:2);Sarcosine,N-(phosphonoamidino)-,disodium salt;Glycine,N-[imino(phosphonoamino)methyl]-N-methyl-,disodium salt;Disodium creatine phosphate;Disodium phosphocreatine;Phosphocreatine disodium;Disodium [N′-(carboxymethyl)-N′-methylcarbamimidamido]phosphonate;Disodium 2-[methyl-(N′-phosphonatocarbamimidoyl)amino]acetic acid;1159882-55-9
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CAS No:
Safety Information
3
20/21/22-36/37/38
22-24/25-36-26
Xn
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 44 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Disodium creatine phosphate Use and Manufacturing
Detection of creatine kinase substrate
Glycine, N-[imino(phosphonoamino)methyl]-N-methyl-, sodium salt (1:?): INACTIVE
Computed Properties
Molecular Weight:233.10
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:233.01775168
Monoisotopic Mass:233.01775168
Topological Polar Surface Area:139
Heavy Atom Count:14
Complexity:276
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Creatine phosphate plays an important role in the energy metabolism of muscle contraction. It is the chemical energy reserve of myocardial and skeletal muscles and is used for the resynthesis of ATP. The hydrolysis of ATP provides energy for the contraction process of actomyosin. Insufficient energy supply caused by slowed oxidative metabolism is an important factor in the formation and development of myocardial cell damage. Insufficient creatine phosphate levels have important clinical significance in the damage of myocardial contractility and functional recovery ability. Maintaining the level of high-energy phosphate compounds has become the basic principle of various methods to limit myocardial damage, and it is also the basis for cardiac metabolic protection. Animal experiments and human cardiac arrest experiments have shown the role of sodium creatine phosphate and its possibility of protecting the myocardium.
Registered Holders
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Amicogen(China) Biopharm Co., Ltd.
Active
China
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Qidong Huatuo Pharmaceutical Co., Ltd.
Active
China
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Hainan Zhuoke Pharmaceutical Co., Ltd.
Active
China
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