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Epipropidine

Epipropidine structure

CAS No:
5696-17-3
Formula:
C16H28N2O2
Chemical Name:
Epipropidine
Synonyms:
4,4′-Bipiperidine,1,1′-bis(2-oxiranylmethyl)-;4,4′-Bipiperidine,1,1′-bis(2,3-epoxypropyl)-;4,4′-Bipiperidine,1,1′-bis(oxiranylmethyl)-;1,1′-Bis(2-oxiranylmethyl)-4,4′-bipiperidine;NSC 56308;Epoxypropidine;Lilly 28002;Epipropidine;1,1′-Bis(oxiranylmethyl)-4,4′-bipiperidine;Eponate;1,1′-Bis(2,3-epoxypropyl)-4,4′-bipiperidine;1,1′-Di(2,3-epoxypropyl)-4,4′-bipiperidine
Categories:
Active Pharmaceutical Ingredients > Antineoplastic Agents

Description

Epipropidine is an epoxide and alkylating agent with antineoplastic activity. Epipropidone is not used clinically due to its unstable nature.

Epipropidine Basic Attributes

Molecular Weight：

280.409

Exact Mass：

280.41

EC Number：

227-170-0

UNII：

T3RCY5OD7A

NSC Number：

56308

NCI Thesaurus Code：

C78083

Characteristics

PSA：

31.5

XLogP3：

1.08380

Density：

1.146g/cm3

Boiling Point：

387.4ºC at 760mmHg

Flash Point：

112.2ºC

Refractive Index：

1.553

Toxicity：

LD50 intravenous in mouse: 74mg/kg

Epipropidine Use and Manufacturing

Antineoplastic.

Computed Properties

Molecular Weight:280.41
XLogP3:1.2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:280.215078140
Monoisotopic Mass:280.215078140
Topological Polar Surface Area:31.5
Heavy Atom Count:20
Complexity:290
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes