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Home > Encyclopedia > Collagenase

Collagenase

pharmaceutical raw materials
Collagenase structure

Collagenase 

structure
  • CAS No:

    9001-12-1

  • Chemical Name:

    Collagenase

  • Synonyms:

    Collagenase;Collagenase A;Collagen peptidase;Collagen protease;Nucleolysin;Soycollagestin;Metallocollagenase;Collagenase type I;Collagenase type 1;Collagenase I;Collagenase 1;Morikraz;Matrix metalloprotease MMP-ABT;Euphaulysin;Collagenolytic enzymes;Endoenzymes,collagenolytic;Enzymes,collagen-degrading;Collalitine;Collalatine;Collagenase type A;Preprocollagenase;39433-96-0;106043-70-3;308064-64-4

  • Categories:

    Biochemical Engineering  >  Enzymes and Coenzymes Drugs

Description

A rare proteinase that catalyzes the hydrolysis of collagen. Collagenase activity has been demonstrated in several venoms of crotalid and viperid snakes and it occurs in certain species of clostridium.

Collagenase Basic Attributes

849.4494

812.418091

232-582-9

3507907000

Characteristics

25.8

21.9

light brown powder

Soluble in aqueous buffers.

2-8°C

Safety Information

NONH for all modes of transport

1

36/37/38-42

22-24-26-36/37

Xn

P261-P305 + P351 + P338-P342 + P311

H315-H319-H334-H335

|Danger|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P285, P302+P352, P304+P340, P304+P341, P305+P351+P338, P312, P321, P332+P313, P337+P313, P342+P311, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 125 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Collagenase Use and Manufacturing

Uses

In investigation of the structure and biosynthesis of collagen; in dispersion of cells for tissue culture studies.

Collagenase: ACTIVE|XU - indicates a substance exempt from reporting under the Chemical Data Reporting Rule, (40 CFR 711).

Computed Properties

Molecular Weight:849.4
XLogP3:21.9
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:14
Exact Mass:848.78865120
Monoisotopic Mass:848.78865120
Topological Polar Surface Area:25.8
Heavy Atom Count:62
Complexity:1490
Defined Atom Stereocenter Count:12
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Not yet clear

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Registered Holders

  • Nordmark Pharma GmbH

    Germany Germany
    Active
  • GRAND LIFE SCIENCES (ANSHAN) CO LTD

    United States United States
    Active

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