Collagenase
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Collagenase
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CAS No:
9001-12-1
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Chemical Name:
Collagenase
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Synonyms:
Collagenase;Collagenase A;Collagen peptidase;Collagen protease;Nucleolysin;Soycollagestin;Metallocollagenase;Collagenase type I;Collagenase type 1;Collagenase I;Collagenase 1;Morikraz;Matrix metalloprotease MMP-ABT;Euphaulysin;Collagenolytic enzymes;Endoenzymes,collagenolytic;Enzymes,collagen-degrading;Collalitine;Collalatine;Collagenase type A;Preprocollagenase;39433-96-0;106043-70-3;308064-64-4
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CAS No:
Description
A rare proteinase that catalyzes the hydrolysis of collagen. Collagenase activity has been demonstrated in several venoms of crotalid and viperid snakes and it occurs in certain species of clostridium.
Safety Information
NONH for all modes of transport
1
36/37/38-42
22-24-26-36/37
Xn
P261-P305 + P351 + P338-P342 + P311
H315-H319-H334-H335
|Danger|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P285, P302+P352, P304+P340, P304+P341, P305+P351+P338, P312, P321, P332+P313, P337+P313, P342+P311, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 125 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Collagenase Use and Manufacturing
In investigation of the structure and biosynthesis of collagen; in dispersion of cells for tissue culture studies.
Collagenase: ACTIVE|XU - indicates a substance exempt from reporting under the Chemical Data Reporting Rule, (40 CFR 711).
Computed Properties
Molecular Weight:849.4
XLogP3:21.9
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:14
Exact Mass:848.78865120
Monoisotopic Mass:848.78865120
Topological Polar Surface Area:25.8
Heavy Atom Count:62
Complexity:1490
Defined Atom Stereocenter Count:12
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Not yet clear
Registered Holders
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Nordmark Pharma GmbH
Active![Germany]()
Germany
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GRAND LIFE SCIENCES (ANSHAN) CO LTD
Active![United States]()
United States
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