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Poly(dimethylsiloxane)

Poly(dimethylsiloxane) structure

CAS No:
9016-00-6
Formula:
(C2H6OSi)n
Chemical Name:
Poly(dimethylsiloxane)
Synonyms:
Poly[oxy(dimethylsilylene)];Octamethylcyclotetrasiloxane polymer,SRU;Poly(octamethylcyclotetrasiloxane),SRU;Hexamethylcyclotrisiloxane polymer,SRU;Hexamethylcyclotrisiloxane homopolymer,SRU;Octamethylcyclotetrasiloxane homopolymer,SRU;Dimethyl siloxane;Dimethylpolysiloxanes;Dimethylsilicone;Poly(dimethylsiloxane);Dimethylsilanediol homopolymer,SRU;Di-Me siloxane,SRU;KS 839;TSHR 100;Dimethylsiloxane homopolymer,SRU;KT 2000B;KF 96A50;Dimethylsilanediol polymer,sru;Dimethyl siloxane,sru;ER 84002;AF 72;AF 60;Rhodorsil RH 414;EP 84002;Versaflow 102;KF 96H60000;Rhodorsil 47V500000;TSF 451-10ER;AF 60 (siloxane);SH 200-20;SH 200-0.65;SH 200-50;SH 200-500;SR 436;SM 7060;SM 8701;SH 8710;TSM 640;TSM 641;TSM 630;L 45/50CS;KS 9001;Tegiloxan 3;X 7-5203;WS 101;SH 7063;SM 2140;SM 2068A;KM 787;KM 788;PMS 5;L 45;NUC-L 45;NUC Silicone L 45;SPB 1;RP 60;KM 893;KE 9705;Dow Corning 6-1104;DC 6-1104;SR 2408;TSF 451;DKQ 8-770;SXP 3;ASI 100 Methyl;PS 049.5;Delomet 2301WS;SM 2163;SH 7028;A 50;Silicone Fluid A 50;A 50 (silicone);X 92-122;Q 2-1484;Nusil PLY 7501;KissCote;RP 6;Dow Corning 1400;TSM 648;R 170 (silicone);SM 7027;Viscasil 10M;R 170;AF 9000;KF 92;BY 27-003;BY 27-007;Modarez SPA;Silicone Oil 350;KS 717;OV 1;Sandoperm MEJ;Viscasil 30000;Poly(dimethylsiloxane),SRU;Polydimethylsiloxane;Emulsion 75;Lurol PP 5228;TEX 103;Dow Corning 75;TSF 451-10000ST;SD 8000;VP 7660;TSF 451-100CS;Rhodorsil HP 1055U;9049-10-9;9063-73-4;9087-48-3;9087-49-4;12619-98-6;12620-09-6;12680-27-2;12680-28-3;37200-44-5;37221-89-9;37267-73-5;37340-53-7;39457-57-3;39476-41-0;51569-26-7;51888-90-5;51910-51-1;52232-96-9;52622-98-7;53125-20-5;53239-64-8;54351-38-1;54351-90-5;56730-54-2;57486-07-4;57679-15-9;58391-68-7;60440-54-2;60842-63-9;90250-23-0;109946-28-3;110616-98-3;118731-39-8;123243-00-5;123515-75-3;141093-32-5;231934-55-7;247174-77-2;387334-72-7;387334-73-8;387334-74-9;444348-83-8;697286-36-5;2319702-71-9
Categories:
Cosmetic Ingredient > Skin Conditioning

Description

colourless liquid with a viscosity, The polydimethylsiloxane materials are excellent examples of silicones because of their chemical properties and widespread industrial use. They can be manufactured as gels, resins, fluids, or elastomers, depending on the cross-linking characteristics. Toxicity testing using polydimethylsiloxane compounds on animals has found little, if any, harmful effects associated with chronic exposure. These tests include oral dosing and teratogenicity testing (Cutler et

Dimethylpolysiloxane is a colorless odorless liquid, Floats on water. (USCG, 1999)|COLOURLESS OILY LIQUID.

Dimethylpolysiloxane is a colorless odorless liquid, Floats on water. (USCG, 1999)

Poly(dimethylsiloxane) Basic Attributes

Molecular Weight：

74.15390

Exact Mass：

74.01880

EC Number：

256-344-9|618-493-1

ICSC Number：

0318

DSSTox ID：

DTXSID40274001

HScode：

39100000

Characteristics

PSA：

17.07000

XLogP3：

0.66800

Density：

0.76-0.971 g/cm³

Melting Point：

-50 °C

Boiling Point：

155-220°C

Flash Point：

63°C

Refractive Index：

1.4035

Water Solubility：

H2O: INsoluble

Vapor Pressure：

5 mm Hg ( 20 °C)

Air and Water Reactions：

Insoluble in water.

Reactive Group：

Siloxanes

Reactivity Profile：

DIMETHYLPOLYSILOXANE is a weak reducing agent.

Safety Information

Transport codes：

UN 1993

wgk germany：

hazard class code：

R36/37/38

safety instructions：

S24/25

RTECS Number：

TQ2690000

Stability/Shelf Life：

Stable. Flammable or combustible. Flammability depends upon extent of polymerization. Incompatible with strong oxidizing agents.

Hazard Statements：

H413

Fire Hazards：

Combustible.

GHS Classification：

|Warning|H319 (30.48%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]|P264, P273, P280, P305+P351+P338, P337+P313, and P501|Aggregated GHS information provided by 430 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Fire Fighting：

Fire Extinguishing Agents Not to Be Used: Water may be ineffective. Fire Extinguishing Agents: Foam, dry chemical, carbon dioxide. (USCG, 1999)|Use powder, AFFF, foam, carbon dioxide.

Personal Protective Equipment：

Safety goggles. (USCG, 1999)

Spillage Disposal：

Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Inhalation Risk：

No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.

Effects of Short Term Exposure：

The substance is irritating to the eyes.

Fire Prevention：

NO open flames.

Inhalation Prevention：

Use ventilation.

Skin Prevention：

Protective gloves.

Eye Prevention：

Wear safety spectacles.

Drug Information

Health Hazards：

Contact of liquid with eyes may cause temporary discomfort. Does not irritate skin. Harmless when ingested. (USCG, 1999)

First Aid：

Except for eye contact, exposures generally do not require treatment. EYES: flush with water. (USCG, 1999)

Fresh air, rest.

Remove contaminated clothes. Rinse skin with plenty of water or shower.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

MeSH Entry Terms：

dimethicone

Exposure Routes：

The substance can be absorbed into the body by inhalation.

Symptoms：

Redness. Pain.

Poly(dimethylsiloxane) Use and Manufacturing

Water-repellent, protective creams & lotions.

Computed Properties

Molecular Weight:74.15
Hydrogen Bond Acceptor Count:1
Exact Mass:74.018791345
Monoisotopic Mass:74.018791345
Topological Polar Surface Area:17.1
Heavy Atom Count:4
Complexity:29
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

This product can change the surface tension of bubbles and make them burst, thereby eliminating bubbles in the respiratory tract. In acute pulmonary edema, this product can improve gas exchange by eliminating bubbles in the deep respiratory tract and alveoli.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Dimethicone aerosol
Ingredients	Dimethicone polymer.
Indication	Not yet clear.
Specifications	Each bottle has a total volume of 18g and contains 0.15g of dimethicone
Manufacturer	Zigong Honghe Pharmacy Co., Ltd.

Dimethicone Powder
Ingredients	Chemical name: dimethylsiloxane polymer. Its chemical structure is as follows: Molecular formula: CH3 (C2H6SiO) nSiC3H9
Indication	If you are taking other medications, please consult your physician or pharmacist before using this product.
Specifications	5g:0.3g;30g:1.8g

Registered Holders

RIOCARE INDIA PRIVATE LTD

United States
Active
RIOCARE INDIA PVT LTD

United States
Active
DOW CORNING CORP.

Brazil
Inactive

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Guide of Poly(dimethylsiloxane)

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
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Poly(dimethylsiloxane)

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