Psoralen
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Psoralen
structure -
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CAS No:
66-97-7
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Formula:
C11H6O3
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Chemical Name:
Psoralen
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Synonyms:
7H-Furo[3,2-g][1]benzopyran-7-one;Furocoumarin;Ficusin;Furo[4′,5′:6,7]coumarin;Psoralen;Psoralene;2-Propenoic acid,3-(6-hydroxy-5-benzofuranyl)-,δ-lactone;Furo[2′,3′:7,6]coumarin;6,7-Furanocoumarin;NSC 404562;Prosuler
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CAS No:
Description
Psoralen(Furocoumarin) is an active ingredient from Fructus Psoraleae; has anticancer activity.IC50 value:Target:in vitro: Psoralen dosages of 1-10 μM exhibited low cytotoxicity toward chondrocytes. However, a dosage of 100 μM suppressed the proliferation of chondrocytes. Different concentrations of psoralen treatments on chondrocytes revealed that GAG and Type II collagen synthesis increased, especially at 100 μM, by 0.39-fold and 0.48-fold, respectively, on day 3, and by 0.51-fold and
Characteristics
39.4
2.3
Solid
1.4±0.1 g/cm3
163-164 °C
130-140 °C
173.1±23.7 °C
1.667
65.16mg/L(25 ºC)
2-8°C
5.4X10-6 mm Hg at 25 °C (est)
Safety Information
NONH for all modes of transport
3
22-36/37/38
26
LV0944000
Xn
Stable under recommended storage conditions.
P261-P305 + P351 + P338
H302-H315-H319-H335
Psoralen Use and Manufacturing
As photochemical probe in biological systems:P.-S. Song, C.-N. Ou, Ann. N.Y. Acad. Sci. 346, 355 (1980).
Computed Properties
Molecular Weight:186.16
XLogP3:2.3
Hydrogen Bond Acceptor Count:3
Exact Mass:186.031694049
Monoisotopic Mass:186.031694049
Topological Polar Surface Area:39.4
Heavy Atom Count:14
Complexity:284
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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