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Calcium aspirin

Calcium aspirin structure

Calcium aspirin 

structure
  • CAS No:

    69-46-5

  • Formula:

    C9H8O4.1/2Ca

  • Chemical Name:

    Calcium aspirin

  • Synonyms:

    Benzoic acid,2-(acetyloxy)-,calcium salt (2:1);Salicylic acid acetate,calcium salt;Benzoic acid,2-(acetyloxy)-,calcium salt;Algisal;Aspirin calcium salt;Aspirin calcium;Calcium acetylsalicylate;Calcium aspirin;Dispril;Disprin;Kalmopyrin;Kalsetal;Solprin;Soluble aspirin;Tylcalsin;Tylocalsin;Acetylsalicylic acid calcium salt;2-(Acetyloxy)benzoic acid calcium salt;Cal-Aspirin;Solaspin;Ascal;Calcium 2-acetoxybenzoate;Uniprin;Febrosanal;Renolon;Hegemonal;Bamyl;1972607-13-8

Description

The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)

Calcium aspirin Basic Attributes

398.37700

398.03100

200-707-6

WOD7W0DGZS

DTXSID80219037

Characteristics

105.20000

2.46600

321.4ºCat 760 mmHg

131.2ºC

Drug Information

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)|Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes. (See all compounds classified as Cyclooxygenase Inhibitors.)|Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN. (See all compounds classified as Fibrinolytic Agents.)|Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system. (See all compounds classified as Platelet Aggregation Inhibitors.)|Drugs that are used to reduce body temperature in fever. (See all compounds classified as Antipyretics.)

2-(Acetyloxy)benzoic Acid

Computed Properties

Molecular Weight:398.4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:398.0314583
Monoisotopic Mass:398.0314583
Topological Polar Surface Area:133
Heavy Atom Count:27
Complexity:206
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

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